Search Results - neurological+disorders

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Positive Unlabeled Learning With Bias Mitigation for Fair Prediction of Undiagnosed Alzheimer’s Disease (Case No. 2025-113)

Summary: UCLA researchers in the Department of Neurology have developed a software to predict the diagnosis of Alzheimer’s Disease without racial or ethnic biases. Background: Alzheimer’s Disease (AD) represents a major health and economic challenge in the United States. Despite its prevalence, Alzheimer’s remains significantly...

Published: 2/14/2025 | Inventor(s): Timothy Chang

Keywords(s): Alzheimers disease, artificial intelligence/machine learning models, electronic health records (EHR), medical bias reduction, Neurodegeneration Alzheimer's Disease Predictive Testing, neurological disorders, Neurology, personalized medicine

Category(s): Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Data Analytics, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing, Software & Algorithms > Programs, Diagnostic Markers > Aging, Therapeutics > CNS and Neurology

Electrical Stimulation for Acute Stroke (Case No. 2020-787)

Summary: Researchers at the UCLA Department of Neurology have developed an individualized method of delivering non-invasive electrical stimulation to treat acute human ischemic stroke. Background: Stroke is a leading cause of mortality and morbidity across the world. Over 80% of strokes are ischemic due to blockage of blood vessels, causing a low...

Published: 2/14/2025 | Inventor(s): Mersedeh Bahr Hosseini, Jeffrey Saver, Marom Bikson

Keywords(s): Acute ischemic stroke, CNS Rehabilitation, Electrical, Electrical Engineering, Electrical stimulation, Neurocognitive, Neuroimaging, Neurointervention, neurological disorders, Neurology, Neuromodulation, Neuron, Neuropathology, Neuropsychological Test, neuroscience, Neurostimulation, Neurosurgery, soft electrical circuits, Stroke, Stroke Geriatrics Energy Accounting Local Area Network, stroke rehabilitation, stroke therapeutics, Transcutaneous Electrical Nerve Stimulation

Category(s): Electrical, Electrical > Flexible Electronics, Medical Devices, Medical Devices > Cardiac, Medical Devices > Hospital Systems

A Tissue-Like Multimodal Neural Probe (Case No. 2024-108)

Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel self-softening and biocompatible polymer to be used in a neural probe. Background: Implantable bioelectronics are revolutionizing the diagnosis and treatment of neurological and neuropsychiatric disorders. Compared with noninvasive approaches,...

Published: 3/7/2025 | Inventor(s): Anne Andrews, Qibing Pei, Zhixin Xie, Chuanzhen Zhao

Keywords(s): bioelectronics, neural stimulation, Neuroimaging, Neurointervention, neurological disorders, Neuromodulation, Neuropsychological Test, Polymer, Smart Material, soft robotics, thermal stability, Tissue (Biology)

Category(s): Chemical, Chemical > Polymers, Medical Devices > Neural Stimulation, Therapeutics > CNS and Neurology, Materials > Nanotechnology

Intelligent Stent System for Chronic On-Demand Drug Delivery (Case No. 2021-069)

Summary: UCLA researchers in the Department of Neurology have developed an intelligent stent system for chronic on-demand drug delivery, addressing the challenge of the blood-brain barrier hindering drug therapy in the central nervous system. Background: The blood-brain barrier poses a significant obstacle to effective drug delivery to the central...

Published: 2/14/2025 | Inventor(s): Jose Morales, Haotian Lu, Huachen Cui, Xiaoyu Zheng

Keywords(s): blood flow management, blood-brain barrier, Drug, Drug Delivery, Drug monitoring, Invasiveness Of Surgical Procedures, MEMS, minimally invasive device, minimally invasive drug delivery systems, neural signals, neural stimulation, Neurocognitive, Neurodegeneration, neurological disorders, Neurology, neuro-oncology, Neuropathology, Neurosurgery, non-invasive, non-invasive drug monitoring, on-demand drug delivery, Pharmaceutical Drug, piezoelectric ultrasound transducers

Category(s): Platforms, Platforms > Drug Delivery, Medical Devices, Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Oncology, Therapeutics > Musculoskeletal Disease

A System for Detecting Ventriculoperitoneal Shunt Failure (Case No. 2023-057)

Summary: UCLA researchers in the David Geffen School of Medicine and Department of Neurosurgery have created a novel ventriculoperitoneal shunt failure detection system that can alert patients and healthcare providers to prevent life-threatening emergencies. Background: Each year, an estimated 30,000 ventriculoperitoneal (VP) shunts are surgically...

Published: 2/14/2025 | Inventor(s): Geoffrey Colby, David Zarrin

Keywords(s): catheter, cerebrospinal fluid (CSF), CSF disorders, early alert system, elevated intracranial pressure, extraventricular drain, hydrocephalus, intracranial hypertension, intracranial pressure, neurological disorders, ventricular system, ventriculoperitoneal, ventriculoperitoneal shunt failure

Category(s): Medical Devices, Medical Devices > Surgical Tools, Medical Devices > Monitoring And Recording Systems, Platforms, Platforms > Diagnostic Platform Technologies, Electrical, Electrical > Sensors, Electrical > Instrumentation