Search Results - organoids

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Human Glioblastoma Model (UCLA Case No. 2023-273/2024-151)

UCLA researchers in the Department of Biological Chemistry have developed a novel method to study glioblastoma using human brain organoids. BACKGROUND: The National Institutes of Health defines glioblastoma as the most malignant and pervasive subtype of glioma, or glial-based cancer, and report that it is the most common primary brain tumor in adults....

Published: 6/18/2024 | Inventor(s): Aparna Bhaduri

Keywords(s): Brain cancer, Brain organoid, Brain Tumor, Cancer, Glioblastoma, Organoids

Category(s): Therapeutics > CNS and Neurology, Therapeutics > Oncology

Development of Novel Compounds to Suppress Neuronal Stress and Cross the Blood Brain Barrier (UCLA Case No. 2021-165)

SUMMARY: An interdisciplinary group of UCLA researchers have developed and validated a library of compounds that alleviate symptoms of Rett Syndrome and hold enormous therapeutic potential for the long-term treatment of other intellectual disability syndromes. BACKGROUND: Intellectual disability (ID) affects more than 100 million people globally and...

Published: 5/8/2024 | Inventor(s): William Lowry, Michael Jung, Xiaoguang Liu, Elena Korsakova

Keywords(s): blood-brain barrier, Drug, intellectual disability, Organoids, senescence

Category(s): Therapeutics > CNS and Neurology, Life Science Research Tools, Diagnostic Markers > Targets And Assays

Multiwell Plate-Based Flow Culture for Improving the Quality of 3D Tissues (Case No. 2022-067)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a simple, innovative method for growing 3D cell cultures with improved organoid differentiation and reduced hypoxia-induced cell death. TITLE: Multiwell Plate-Based Flow Culture for Improving the Quality of 3D Tissues Background: 3D tissue culture,...

Published: 10/23/2024 | Inventor(s): Neil Lin, Marie Payne

Keywords(s): 3D Printing, Biofilm, Biomaterial 3D Printing, Biomedical Engineering, Cancer, cancer detection, Cancer Immunotherapy, Cell and tissue culture, Cell Culture, Cellular agriculture, Cultured meat, iPS/stem cells, Laminar flow, Microwell plates, organogenesis, Organoids, Personalized Pharmacotherapy, Pharmaceutical testing, Stem Cells / Regenerative Medicine, Tissue (Biology), tissue detection, Tissue Engineering, Tissue sedimentation

Category(s): Life Science Research Tools > Lab Equipment, Life Science Research Tools, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Therapeutics, Therapeutics > Oncology