Search Results - metastasis

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Analoging and SAR-Based Chemical Approach to Improve the Therapeutic Potency of Small-Molecule Inhibitors of Metastasis (UCLA Case No. 2024-116)

UCLA researchers in the Department of Molecular and Medical Pharmacology have developed an analoging and SAR-based chemical approach to generate novel, safe, and effective small-molecule inhibitors for preventing and treating cancer metastasis. BACKGROUND: The limited understanding of the biological mechanisms underlying metastasis in clear cell renal...

Published: 5/14/2025 | Inventor(s): Lily Wu, Moe Ishihara, Robert Damoiseaux, Stuart Conway

Keywords(s): Cancer, Metastasis, Oncology (Small Molecules, Peptides and Antibodies), Small molecule therapeutics, small molecules

Category(s): Therapeutics > Oncology

Syringe Stabilization Device for Ultrasound-Guided Procedures (UCLA Case No. 2023-045)

Summary: UCLA researchers in the Department of Surgery have developed a novel, minimally invasive ultra-sounded guided metastatic mouse model and device enabling more secure and precise usage of in-plane ultrasound imaging of needles. Background: Cancer is the second leading cause of death globally and in the United States. Pancreatic cancer remains...

Published: 2/14/2025 | Inventor(s): Amanda Labora

Keywords(s): Breast Cancer, Cancer, cancer detection, Cancer Immunotherapy, Catheterization, In-plane ultrasound, Intratumoral drug delivery, Metastasis, metastatic mouse model, Mouse model, Orthotopic cancer models, Pancreatic cancer, Preclinical model development, Preclinical surgical innovation

Category(s): Life Science Research Tools, Life Science Research Tools > Animal Imaging, Life Science Research Tools > Animal Models, Medical Devices > Medical Imaging, Therapeutics, Therapeutics > Oncology, Medical Devices > Medical Imaging > Ultrasound