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Intelligent, Adaptive, and Multimodal Data-Driven Epileptogenic Zone Identification and Cognitive Function Mapping Platform (UCLA Case No. 2023-214)

Summary: UCLA researchers in the Departments of Neurology and Electrical and Computer Engineering have developed a data-driven, deep learning-powered software platform to localize epileptogenic tissues in the brain and cognitively map nearby regions. Background: According to the World Health Organization, 50 million people around the world suffer...

Published: 8/1/2025 | Inventor(s): Vwani Roychowdhury, Hiroki Nariai, Richard Staba, Yipeng Zhang

Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, Artificial Neural Network, Biomonitoring, Brain Mapping, Condition monitoring, Deep Learning, Digital Health, Digital Pathology, Electroencephalography (EEG), Epilepsy, Hospital Systems And Devices, Medical Device, Medical Devices and Materials, Monitoring (Medicine), Monitoring And Recording Systems, MRI, PET, remote monitoring, Software, Software & Algorithms

Category(s): Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems

Positron Emission Tomography Guided Delivery of Mitochondrial Complex I Inhibitors (UCLA Case No. 2020-163)

UCLA researchers in the David Geffen School of Medicine Division of Pulmonary and Critical Care Medicine have developed a novel use of the positron emission tomography (PET) tracer [18F]FBnTP to guide the delivery of mitochondrial complex I inhibitors for the treatment of lung cancers.BACKGROUND: The mitochondria are essential regulators of cellular...

Published: 7/17/2025 | Inventor(s): David Shackelford, Seyed Saman Sadeghi Hosseini, Milica Momcilovic

Keywords(s): Diagnostic Markers & Platforms, Imaging, Medical Imaging, PET, Respiratory & Pulmonary

Category(s): Medical Devices > Medical Imaging > PET, Therapeutics > Oncology, Therapeutics > Respiratory And Pulmonary

2017-450 MICROSCALE DEVICE AND METHOD FOR PURIFICATION OF RADIOPHARMACEUTICALS

Microscale Device and Method for Purification of RadiopharmaceuticalsTech ID: 30310 / UC Case 2017-450-0SUMMARYUCLA researchers from the Departments of Molecular & Medical Pharmacology and Bioengineering have developed a novel method for the purification of radiopharmaceuticals for the on-demand production of positron emission tomography (PET) tracers.BACKGROUNDPositron...

Published: 7/17/2025 | Inventor(s): Michael van Dam, Seunghyun Noel Ha, Jason Jones, Jimmy Ly, Stephen Liu, Shilin Cheung

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Medical Imaging, PET

Category(s): Diagnostic Markers, Medical Devices > Medical Imaging, Platforms > Diagnostic Platform Technologies, Medical Devices > Medical Imaging > PET

2017-380 DEVICE AND METHOD FOR MICROSCALE CHEMICAL REACTIONS

Device and Method for Microscale Chemical ReactionsTech ID: 30291 / UC Case 2017-380-0SUMMARYUCLA researchers in the Departments of Bioengineering and Molecular and Medical Pharmacology have developed a passive microfluidic reactor chip with a simplified design that is less costly than existing microfluidic chips.BACKGROUNDAlthough positron emission...

Published: 7/17/2025 | Inventor(s): Michael van Dam, Jia Wang

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Medical Imaging, PET

Category(s): Diagnostic Markers, Medical Devices > Medical Imaging, Platforms > Diagnostic Platform Technologies, Medical Devices > Medical Imaging > PET

2017-185 METHOD FOR CONCENTRATION AND FORMULATION OF RADIOPHARMACEUTICALS

Method For Concentration And Formulation Of RadiopharmaceuticalsTech ID: 30269 / UC Case 2017-185-0SUMMARYResearchers at the UCLA Department of Medical and Molecular Pharmacology have developed a compact microfluidic device that is able to achieve rapid concentration and/or reformulation of PET tracers after HPLC purification.BACKGROUNDPositron emission...

Published: 7/17/2025 | Inventor(s): Michael van Dam, Philip Hongsean Chao

Keywords(s): Life Science Research Tools, Medical Imaging, Microfluidics And Mem's, PET

Category(s): Life Science Research Tools, Life Science Research Tools > Microfluidics And Mems, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > PET

2016-680 AUTOMATED PHANTOM IMAGE ASSESSMENT TO CONFIRM MACHINE PERFORMANCE AND CALIBRATION

Case No. 2016-680SUMMARYUCLA researchers in the Department of Radiology have developed a method for automated calibration of phantom images.BACKGROUNDPhantom imaging is a routine procedure used in different medical imaging methods such as magnetic resonance imaging (MRI), computerized tomography (CT), positron emission tomography (PET) and ultrasound....

Published: 7/3/2025 | Inventor(s): Matthew Brown, Michael Mcnitt-Gray, Pechin Lo, Muhammad Wahi Anwar

Keywords(s): CT, Medical Imaging, MRI, PET, Ultrasound

Category(s): Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > CT, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging > PET, Medical Devices > Medical Imaging > Ultrasound

2014-965 A NEW HUMAN-MONITOR INTERFACE FOR INTERPRETING CLINICAL IMAGES

A New Human-Monitor Interface For Interpreting Clinical ImagesCase No. 2014-965-0SUMMARYUCLA researchers in the Department of Radiological Sciences have invented a novel interactive tool that can rapidly focus and zoom on a large number of images using eye tracking technology.BACKGROUNDWith the development of digital workstations, radiologists have...

Published: 2/14/2025 | Inventor(s): Dieter Enzmann, Osman Ratib

Keywords(s): Bioinformatics, CT, Image Processing, Life Science Research Tools, Medical Imaging, MRI, PET, Software, Software & Algorithms, Ultrasound

Category(s): Software & Algorithms > Image Processing, Life Science Research Tools, Software & Algorithms, Medical Devices > Medical Imaging, Software & Algorithms > Data Analytics, Medical Devices > Medical Imaging > CT, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging > PET, Medical Devices > Medical Imaging > Ultrasound, Software & Algorithms > Bioinformatics, Software & Algorithms > Programs

2008-836 IMPLEMENTATION OF MATHEMATICAL CONSTRAINTS - ITERATIVE METHODS FOR DOSE REDUCTION AND IMAGE ENHANCEMENT IN TOMOGRAPHY

Case No. 2008-836SUMMARYUCLA researchers have developed an algorithm that enables construction of 3D images from tomographic data through iterative methods with the incorporation of mathematical constraints. This methodology is an improvement over conventional techniques as it allows for radiation dose reduction and improved resolution.BACKGROUNDTomographic...

Published: 7/17/2025 | Inventor(s): Jianwei Miao, Benjamin Pooya Fahimian

Keywords(s): CT, Image Processing, Medical Imaging, PET, Software & Algorithms

Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > CT, Medical Devices > Medical Imaging > PET

2008-030 DRUG CONJUGATED MAGNETONANOPARTICLES FOR VISUALIZATION OF NEOPLASM (ONCOLOGY), CARDIAC IMAGING AND NEUROLOGICAL DISEASES AND DISORDERS...

Case No. 2008-030SUMMARYResearchers at the UCLA Semel Institute for Neuroscience and Human Behavior have developed magnetic nanoparticles (MNPs) functionalized with deoxyglucose that can be used as tissue-specific contrast agents for MRI. These novel MNPs can help physicians and researchers to differentiate neoplastic, epileptic, parkinsonian, or Alzheimer...

Published: 7/17/2025 | Inventor(s): Massoud Akhtari, Jerome Engel

Keywords(s): Animal Imaging, Cns, CT, Life Science Research Tools, Medical Devices and Materials, Medical Imaging, Microscopy And Imaging, MRI, Oncology, PET

Category(s): Life Science Research Tools, Life Science Research Tools > Animal Imaging, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging > CT, Medical Devices > Medical Imaging > PET, Therapeutics > CNS and Neurology, Therapeutics > Oncology

Novel Non-Immunogenic Positron Emission Tomography Gene Reporter (UCLA Case No. 2007-474)

Novel Non-Immunogenic Positron Emission Tomography Gene ReporterTech ID: 30321 / UC Case 2007-474-0SUMMARYUCLA researchers in the Department of Pharmacology and Department of Microbiology, Immunology, & Molecular Genetics have developed a novel positron emission tomography reporter gene to preferentially trap radiolabeled deoxycytidine analogs.BACKGROUNDPositron...

Published: 7/31/2025 | Inventor(s): Owen Witte, Caius Radu, Evan Nair-Gill

Keywords(s): Cell Counting/Imaging, Life Science Research Tools, Medical Imaging, PET, Research Methods

Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Cell Counting And Imaging, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > PET

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