Search Results - robert+modlin

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2019-694 ROLE OF BACTERIAL RNA IN INFLAMMATION IN ACNE

SUMMARY:UCLA researchers in the Department of Dermatology have developed a new treatment for acne that can effectively alleviate the inflammatory response caused by acne-inducing bacteria. BACKGROUND:Acne is a chronic skin disease that was estimated to affect 633 million people globally in 2015, ranking as the 8th most common disease in the world....

Published: 7/19/2023 | Inventor(s): Robert Modlin

Keywords(s):

Category(s): Therapeutics > Dermatology, Therapeutics > Autoimmune, Therapeutics > Inflammation And Inflammatory Diseases

2004-087 Antimicrobial Peptide for the Treatment of Skin Diseases

Antimicrobial Peptide for the Treatment of Skin DiseasesSUMMARYGranulysin peptides are small antimicrobial agents with potent activity against bacteria and inflammation. A pharmaceutical composition comprising granulysin peptides as an active agent is administered therapeutically to a patient suffering from a microbial infection.

Published: 7/19/2023 | Inventor(s): David Eisenberg, Robert Modlin, Jenny Kim, Daniel Anderson, Richard Gallo

Keywords(s): Dermatology, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Dermatology

Polycytotoxic T Cells

Case 2016-676UCLA researchers in the Department of Dermatology have characterized a novel subset of CD8+ T cells, termed polycytotoxic, that mediate killing of intracellular pathogens.BACKGROUNDCD8+ T cells are known to engage in cytotoxic activity, where they use pore-forming proteins and proteases (granzyme B, granulysin, and perforin) to induce apoptosis...

Published: 7/19/2023 | Inventor(s): Robert Modlin, Matteo Pellegrini, Samuel Balin, Steffen Stenger

Keywords(s): Autoimmune, Immunology, Infectious Diseases, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Therapeutics, Diagnostic Markers > Immunology, Therapeutics > Autoimmune, Therapeutics > Infectious Diseases