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Polycytotoxic T Cells

Case 2016-676UCLA researchers in the Department of Dermatology have characterized a novel subset of CD8+ T cells, termed polycytotoxic, that mediate killing of intracellular pathogens.BACKGROUNDCD8+ T cells are known to engage in cytotoxic activity, where they use pore-forming proteins and proteases (granzyme B, granulysin, and perforin) to induce apoptosis...

Published: 7/19/2023 | Inventor(s): Robert Modlin, Matteo Pellegrini, Samuel Balin, Steffen Stenger

Keywords(s): Autoimmune, Immunology, Infectious Diseases, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Therapeutics, Diagnostic Markers > Immunology, Therapeutics > Autoimmune, Therapeutics > Infectious Diseases