Search Results - software+%26+algorithms+%3e+bioinformatics

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Physical Separation of Ultrashort Single-Stranded Cell-Free DNA in Biofluids Using Differential Filtration and Next-Generation Sequencing Pipeline to Detect Methylation Status of Ultrashort Single-Stranded Cell-Free DNA (UCLA 2023-077, 2023-082)

UCLA researchers in the Department of Dentistry have established novel extraction and bioinformatics pipeline of ultrashort single-stranded cell-free DNA for the use in liquid biopsy diagnostics. BACKGROUND: Liquid biopsy is a critical diagnostic tool for various human diseases. The rapid market growth of liquid biopsy is primarily driven by novel...

Published: 7/1/2024 | Inventor(s): David Wong

Keywords(s): Cancer, cell-free DNA, circulating DNA, Diagnostic Markers & Platforms, DNA methylation, liquid biopsy, next generation sequencing (NGS)

Category(s): Software & Algorithms > Bioinformatics, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies

Summary: UCLA researchers have developed a software to accelerate vaccine clinical trial processes by modeling disease behavior and targeting future trial participants. Background: Vaccine clinical trials are time-intensive processes; ones that may be necessary during active pandemics in which time is of short supply. One of the primary factors contributing...

Published: 11/15/2024 | Inventor(s): Akihiro Nishi

Keywords(s): Bioinformatics, Clinical Trial, Live attenuated vaccine, Public Health, Simulation & Modeling, Software & Algorithms, Therapeutics & Vaccines, Vaccines

Category(s): Software & Algorithms > Statistical Models, Software & Algorithms > Bioinformatics

Swabseq Agnostic Diagnostic Platform (Case No. 2023-293)

Summary: UCLA researchers in the Departments of Computer Science and Anatomic Pathology have developed an untargeted NGS diagnostic tool capable of detecting all known and emerging respiratory RNA viruses in a single test, enhancing our capacity to rapidly address public health crises through improved diagnostics. Background: Most clinical diagnostic...

Published: 9/17/2024 | Inventor(s): Eleazar Eskin, Valerie Arboleda

Keywords(s): agnostic detection, Bioinformatics, bioinformatics pipeline, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Test, DNA Sequencing, Medical diagnostics, metagenomic diagnostic platform, meta-genomics, next generation sequencing (NGS), Pathogen, Pathogenesis, Sequencing

Category(s): Platforms, Platforms > Diagnostic Platform Technologies, Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Bioinformatics

2020-471 Altering Cytokine Specificity Through Binding Valency

SUMMARY: UCLA researchers in the Department of Bioengineering have developed valency-mediated cytokine improvements, enabling the development of significantly more specific cytokine therapies. BACKGROUND: Cytokine therapy, in the growing arsenal of immunotherapies, aims to enhance, suppress, or alter the function of certain immune cells in a highly...

Published: 7/19/2023 | Inventor(s): Aaron Meyer

Keywords(s):

Category(s): Life Science Research Tools, Software & Algorithms, Software & Algorithms > Bioinformatics, Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy

2022-223 A Bioanalytics-Enabled and Hollow Microneedle-Based Wearable Technology for Personalized Medicine

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a minimally-invasive wearable device that continuously monitors pharmaceutical concentrations in a user to optimize the drug’s dosage. Background: The annual cost of medication-related morbidity and mortality due to non-optimized pharmacotherapy...

Published: 7/19/2023 | Inventor(s): Sam Emaminejad, Shuyu Lin

Keywords(s): Adverse Drug Reaction, Antibody-Drug Conjugate, Antiviral Drug, Biomonitoring, Blood Glucose Monitoring, Drug, Drug Carrier, Drug Delivery, Drug Delivery Microporous Material, Drug Development, Drug Development Feature Extraction, Drug Discovery, Drug monitoring, Drug Resistance, Drug-Eluting Stent, Extensively Drug-Resistant Tuberculosis, Fine-Needle Aspiration, Gene Combination Drug, Immunosuppressive Drug, interstitial fluid (ISF)-based information, Investigatioal New Drug, Management Of HIV/AIDS Psychoactive Drug, medical automation technology, Medical Device, Medical Devices and Materials, medication customization, medication efficacy, Microneedle array, minimally invasive device, Monitoring (Medicine), Monitoring And Recording Systems, Multiple Drug Resistance, Mutation Drug Design, Nanosensor, Nanostructure, Nanotechnology, non-invasive drug monitoring, personalized dose assessment, Pharmaceutical Drug, Pharmaceutical Drug Ethylene Glycol, Pharmaceutical Drug Opioid Dependence, Prescription Drug, real-time sensing/monitoring/tracking, remote monitoring, sample-to-answer devices, Smart medical device, Therapeutic Drug Monitoring, wearable medical device

Category(s): Mechanical, Mechanical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms > Drug Delivery, Software & Algorithms > Bioinformatics, Software & Algorithms > Artificial Intelligence & Machine Learning, Electrical > Sensors, Materials > Nanotechnology

2021-260: THE INNATE IMMUNE HEALTH SCORE

SUMMARY: UCLA researchers in the Department of Microbiology, Immunology, and Molecular Genetics have developed a strategy to quantitatively assess the functionality of macrophages, a key player of the innate immune system, using a paired experimental and computational strategy. BACKGROUND: The immune system is formed by two major inter-related components,...

Published: 10/4/2024 | Inventor(s): Alexander Hoffmann

Keywords(s):

Category(s): Software & Algorithms > Bioinformatics, Diagnostic Markers > Immunology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Infectious Diseases, Therapeutics > Inflammation And Inflammatory Diseases

2021-354 A MULTI-MODAL CRYPTO/BIO-HUMAN-MACHINE INTERFACE

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an instrument that detects and encrypts a user’s biochemical and biometric data with only a touch of the finger. Background: Human machine interfaces (HMI), such as touchscreens and keyboards, are able to connect users to machines, systems, and...

Published: 7/19/2023 | Inventor(s): Sam Emaminejad, Shuyu Lin, Jialun Zhu, Wenzhuo Yu

Keywords(s): Bioinformatics, Biosensor, Biotechnology, Computer Security, Digital Health, Sensor, Software & Algorithms

Category(s): Software & Algorithms > Bioinformatics, Software & Algorithms > Digital Health, Mechanical > Sensors, Electrical > Sensors, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics, Chemical > Chemical Sensors, Software & Algorithms > Programs

2021-225 An Innovative Dielectric Elastomer and Multilayer Dielectric Elastomer Actuator with High Electrically Induced Actuation Strains

SUMMARY: UCLA researchers in the Department of Materials Science and Engineering have developed a dielectric elastomer and layering process that can produce actuators capable of high strain and high frequency actuation. BACKGROUND: Dielectric elastomers (DE) can act as deformable capacitors that can generate a mechanical movement in response to an...

Published: 7/19/2023 | Inventor(s): Qibing Pei, Erin Askounis, Ye Shi

Keywords(s): Actuator, Capacitor, Dielectric, Elastomer, Electroactive Polymers, Flexible Electronics, Functional Materials, Haptic Technology, Haptic Technology Robotic Surgery, Robotics, Sensors, Smartphone

Category(s): Software & Algorithms, Software & Algorithms > Bioinformatics, Life Science Research Tools, Software & Algorithms > Programs

2022-084 HUMAN LEUKOCYTE ANTIGEN HAPLOTYPE ANALYSIS TOOLKIT (HLA-HAT)

SUMMARY: UCLA researchers in the department of Medicine, Hematology and Oncology have developed software which facilitates the clinically relevant investigation of genetic antigen heterogeneity within human leukocytes BACKGROUND: Human leukocyte antigen system is a critical component of the immune system. A major part of this is a series of genes...

Published: 9/19/2024 | Inventor(s): Katie Campbell

Keywords(s): Algorithm, Allele, Autoimmune Disease, Bioinformatics, Biotechnology, CD3 (Immunology) Human Leukocyte Antigen, Functional Genomics, Genetic Algorithm, Genetic Testing, Immunology, Inflammation, Instrumentation & Analysis, Sequencing, Software, Software & Algorithms

Category(s): Life Science Research Tools, Software & Algorithms, Software & Algorithms > Bioinformatics

2016-638 COPYRIGHT: DIABETES RISK SCREENING USING ELECTRONIC HEALTH RECORDS

SUMMARY: UCLA researchers in the Department of Psychiatry and Biobehavioral Sciences have invented a novel algorithm that uses electronic health records to determine a patient’s risk of having undiagnosed two diabetes mellitus. BACKGROUND: Type two diabetes mellitus, often simply referred to as diabetes, affects 1 in 10 patients in the U.S....

Published: 7/19/2023 | Inventor(s): Ariana Anderson

Keywords(s): Big Data, Bioinformatics, Biotechnology, Diabetes Management, Diabetes Mellitus Type 1, Diabetes Mellitus Type 2, Diagnostic Test, Medical Device, Preventive Medicine, Prognosis, Software, Software & Algorithms

Category(s): Software & Algorithms, Software & Algorithms > Bioinformatics, Software & Algorithms > Data Analytics

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