Search Results - therapeutics+%3e+ophthalmology

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CHST6 Mini Gene - CHST6 Expression Construct With Native Promoter (UCLA Case No. 2023-301)

UCLA researchers from the Department of Human Genetics and Department of Ophthalmology have developed a mini gene encoding a protein which is mutated in macular corneal dystrophy, leading to a potential gene therapy for this disorder. BACKGROUND: Macular corneal dystrophy (MCD) is a rare genetic disease caused by mutations in the CHST6 gene, which...

Published: 11/20/2024 | Inventor(s): Wenlin Zhang, Anthony Aldave

Keywords(s): AAV, Adeno-associated viruses (AAV), Gene Editing Systems, Gene Therapy, genetics, keratinocytes, macular corneal dystrophy, mini gene, mutation, native promoter, Ophthalmology

Category(s): Therapeutics > Ophthalmology, Therapeutics > Gene Therapy And Editing

Anti-Inflammatory Drug Eluting Patches for Treatment of Ocular Injuries (UCLA Case No. 2022-156)

UCLA researchers in Department of Chemical and Biomolecular Engineering developed a visible light crosslinkable hydrogel-based drug delivery platform that can achieve sustainable release of anti-inflammatory drug molecules to address unmet need of drug bioavailability in ocular injury treatment. BACKGROUND: The Centers for Disease Control and Prevention...

Published: 9/26/2024 | Inventor(s): Nasim Annabi

Keywords(s): eye disease, gelpatch, hyaluronic acid, micelles, Nanoparticles, ocular, ocular inflammation, Ophthalmic antibiotics, Ophthalmology

Category(s): Therapeutics > Ophthalmology

System and Methods for Fluidic Control in Ophthalmic Procedures (Case No. 2024-229)

Summary: Researchers in the Mechanical Engineering Department at UCLA developed an innovative mechatronic system that can perform fast and accurate pressure regulation during cataract surgeries. Background: Despite being generally safe and successful, cataract surgery has a complication rate of about 6%, which is concerning given the high volume...

Published: 10/31/2024 | Inventor(s): Tsu-Chin Tsao, Yu-Ting (Kevin) Lai, Aya Barzelay

Keywords(s): biomedical sensors, Intraocular Lens , Ophthalmology, Robotic Surgery

Category(s): Mechanical > Instrumentation, Medical Devices > Hospital Systems, Medical Devices > Surgical Tools, Medical Devices > Monitoring And Recording Systems, Therapeutics > Ophthalmology

Assistive Device to Aid in Identification and Use of Medications (UCLA Case No. 2022-213)

Summary: Researchers in the UCLA Stein Eye Institute have developed a medication assistive device to aid in distinguishing medication bottles and administering medications on the correct schedules for patients, especially those with visual impairment. Background: Many ophthalmic conditions are treated with eye drop medications. These treatments...

Published: 11/15/2024 | Inventor(s): Edmund Tsui, Jie Deng, Holly Huang, Jeffrey Li, Hyeongtaek Nam, Brian Wu

Keywords(s): 3D Printing, Hospital Systems And Devices, Medical Devices and Materials, Monitoring And Recording Systems, Ophthalmology, Therapeutics & Vaccines

Category(s): Medical Devices > Monitoring And Recording Systems, Therapeutics > Ophthalmology

2022-153: In Vivo Biomarkers of Human Limbal Stem Cell Function

SUMMARY: UCLA researchers in the Department of Ophthalmology have identified novel in vivo biomarkers of limbal stem cell function to accurately diagnose and stage limbal stem cell deficiency. BACKGROUND: The cornea, which is the main part of the eye that is responsible for the production of clear vision, is protected from microbes and fluids by the...

Published: 9/5/2023 | Inventor(s): Sophie Deng

Keywords(s):

Category(s): Diagnostic Markers, Therapeutics > Ophthalmology

A Novel Device to Produce Autologous Serum Eye Drops at the Point of Care (Case No. 2021-198)

SUMMARY: UCLA researchers in the Stein and Doheny Eye Institutes have designed a device that can produce autologous serum eye drops at the point-of-care, greatly reducing the cost and complexity of the production process. BACKGROUND: Ocular surface diseases afflict hundreds of millions of people per year worldwide. Autologous serum eye drops benefit...

Published: 9/29/2023 | Inventor(s): Justin Karlin

Keywords(s): Human Serum Albumin, Medical Devices and Materials, Targeted Therapy, Therapeutics & Vaccines

Category(s): Life Science Research Tools > Lab Equipment, Therapeutics > Ophthalmology

2020-483 Device for Mobilizing Cortical Material at Lens Equator during Cataract Surgery

SUMMARYUCLA researchers in the Department of Ophthalmology and Mechanical Engineering have developed an instrument for the complete removal of cortical material during cataract surgery, including material along the lens equator.BACKGROUNDCataract surgery consists of removing, to the greatest extent possible, the cataract from the capsular bag within...

Published: 7/19/2023 | Inventor(s): Jean-Pierre Hubschman, Matthew Gerber, Tsu-Chin Tsao, Jacob Rosen

Keywords(s):

Category(s): Medical Devices > Surgical Tools, Therapeutics > Ophthalmology

2021-038 RAVIR: A Dataset and Methodology for Semantic Segmentation and Quantitative Analysis of Retinal Arteries and Veins in Infrared Reflectance Imaging

SUMMARYUCLA researchers in the Department of Computer Science have developed a method for the semantic segmentation and quantitative analysis of retinal arteries and veins via infrared reflectance retinal imaging (RAVIR).BACKGROUNDRetinal vasculature analysis can be used to help diagnose neurodegenerative disorders and monitor systemic diseases such...

Published: 7/19/2023 | Inventor(s): Demetri Terzopoulos, Steven Schwartz, Hamid Hosseini, Ali Hatamizadeh

Keywords(s):

Category(s): Life Science Research Tools > Microscopy And Imaging, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Diagnostic Markers, Medical Devices > Medical Imaging, Therapeutics > Ophthalmology, Optics & Photonics

2019-995 Mobile Device Application for Bluetooth Beacon Sensors to Monitor Magnification Device Usage

SUMMARY:UCLA researchers in the Department of Ophthalmology have developed a small Bluetooth low energy beacon sensor to monitor low vision patient use of visual assist devices in real-time. BACKGROUND:Rehabilitation for low vision patients includes the use of visual assisting devices such as magnifiers. One in five patients, however, abandon their...

Published: 7/19/2023 | Inventor(s): Ava Bittner

Keywords(s):

Category(s): Software & Algorithms > Digital Health, Electrical > Sensors, Medical Devices > Monitoring And Recording Systems, Therapeutics > Ophthalmology, Electrical > Wireless

2019-853 A Method to Measure Perceptual Thresholds

SUMMARYUCLA researchers in the Department of Psychology have developed a method to accurately measure a patient’s perceptual (visual, auditory, etc.) threshold unaffected by patient response bias. BACKGROUNDThere are more than 200,000 cases of glaucoma in the US every year. Computerized threshold perimetry is the gold standard for visual field...

Published: 7/19/2023 | Inventor(s): Zili Liu

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Ophthalmology

Category(s): Platforms > Diagnostic Platform Technologies, Therapeutics > Ophthalmology

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