Search Results - life+science+research+tools+%3e+animal+models

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2023-123 Systems for Covertly Creating Adverse Health Effects in Subjects

Summary: UCLA researchers in the Division of Physics and Astronomy have developed a less-than-lethal method for covertly creating adverse health effects in human subjects using particular waveforms. Background: Several less-than-lethal techniques for altering or influencing the behavior of target subjects without physical contact have been developed....

Published: 8/21/2023 | Inventor(s):

Keywords(s): electromagnetic, Hardware, Instrumentation, Life Science Research Tools, Security and defense, security imaging

Category(s): Life Science Research Tools > Animal Models, Electrical > Sensors, Electrical > Imaging, Medical Devices > Neural Stimulation

Syringe Stabilization Device for Ultrasound-Guided Procedures (UCLA Case No. 2023-045)

Summary: UCLA researchers in the Department of Surgery have developed a novel, minimally invasive ultra-sounded guided metastatic mouse model and device enabling more secure and precise usage of in-plane ultrasound imaging of needles. Background: Cancer is the second leading cause of death globally and in the United States. Pancreatic cancer remains...

Published: 11/8/2023 | Inventor(s): Amanda Labora

Keywords(s): Breast Cancer, Cancer, cancer detection, Cancer Immunotherapy, Catheterization, In-plane ultrasound, Intratumoral drug delivery, Metastasis, metastatic mouse model, Mouse model, Orthotopic cancer models, Pancreatic cancer, Preclinical model development, Preclinical surgical innovation

Category(s): Life Science Research Tools, Life Science Research Tools > Animal Imaging, Life Science Research Tools > Animal Models, Medical Devices > Medical Imaging, Therapeutics, Therapeutics > Oncology, Medical Devices > Medical Imaging > Ultrasound

2020-120 NOVEL MOUSE MODELS FOR GENETICALLY-DIRECTED SPARSE AND COMPLETE LABELING OF BRAIN CELLS FOR ANALYSIS OF BRAIN CELL BIOLOGY AND PATHOLOGY

Researchers in the Jane and Terry Semel Institute for Neuroscience and Human Behaviors at UCLA have developed four novel reporter mouse lines that illuminate morphologies of genetically-defined neurons and glia and can serve as novel platform for testing candidate therapeutics for neurodevelopmental, psychiatric and age-related brain diseases. The tools...

Published: 7/19/2023 | Inventor(s): William Yang

Keywords(s): Animal Models, Cns, Diagnostic Markers & Platforms, Life Science Research Tools

Category(s): Life Science Research Tools > Animal Models, Platforms > Diagnostic Platform Technologies, Therapeutics > CNS and Neurology

(XN) 2005-059 PTEN Null Cell Lines

PTEN Null Cell LinesBACKGROUNDPTEN (phsosphatase and tensin homolog deleted on chromosome 10) is a tumor suppressor gene identified to be frequently mutated/deleted in various human cancers. Besides carcinogenesis, Pten may play important roles in regulating stem cell activity, insulin action and development. PTEN is a member of the protein tyrosine...

Published: 7/19/2023 | Inventor(s): Hong Wu, Daniel Freeman

Keywords(s): Animal Models, Cell Lines, Life Science Research Tools, Oncology

Category(s): Life Science Research Tools > Animal Models, Life Science Research Tools > Cell Lines, Life Science Research Tools, Therapeutics > Oncology

2011-725 Dual Transgenic Mice for Endothelial Cell Research (Ve-Cadherin Cre-Recombinase - Rosa26r-YFP)

Summary UCLA researchers have developed a dual transgenic animal that enables genetic tracing of endothelial cells and their derivatives. Background Disturbances in endothelial gene expression contribute to vascular morphogenesis and tumor growth. Over the past century, the mouse has emerged as the premier mammalian model system for genetic research....