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AI-Based Wearable Sensor for Dermatology (Case No. 2025-301)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a flexible, cost-effective, AI-enabled wearable sensor that facilitates early, non-invasive diagnosis of allergic contact dermatitis. Background: Allergic contact dermatitis (ACD) is a hypersensitivity reaction of the skin triggered by direct contact...

Published: 8/26/2025 | Inventor(s): Aydogan Ozcan, Shannon Wongvibulson, Paloma Casteleiro Costa, Gyeo-Re Han, Yuzhu Li

Keywords(s): Artificial Intelligence, artificial intelligence augmentation, artificial intelligence/machine learning models, Artificial Neural Network, artificial-intelligent materials, Computer-Aided Diagnosis, deep neural networks (DNN), Dermatology, electrochemical sensors, Medical artificial intelligence (AI), Signal Processing, Signal-To-Noise Ratio, Skin, skin protection, wearable, wearable electronics, wearable medical device, wearable medical devices, wearable sensors, wearable sensors for health

Category(s): Electrical, Electrical > Flexible Electronics, Electrical > Sensors, Medical Devices > Monitoring And Recording Systems, Therapeutics > Dermatology, Diagnostic Markers

Bioelectric Neuromodulation Methods for Hematopoiesis Regulation During Chemotherapy (Case No. 2020-382)

Summary: UCLA researchers in the Department of Bioengineering have developed an electrical neuromodulation method to accelerate recovery from deleterious chemotherapy side effects to improve patient outcome. Background: Chemotherapy works by targeting and killing fast-growing cancer cells using anti-cancer drugs. However, because these drugs lack...

Published: 8/21/2025 | Inventor(s): Wentai Liu

Keywords(s): algorithmic cancer detection, Bladder Cancer, blood cancers, Brain cancer, Breast Cancer, Cancer, cancer antigen, cancer detection, Cancer Immunotherapy, cancer inhibition, cancer metabolism, Cancer stem cells, cancer target, castration resistant prostate cancer, Chemotherapy, head and neck cancer, lympathic cancers, lymphatic cancer, Mesenchymal Stem Cell Derived Cancer Cells, Neuromodulation, non-small cell lung cancer, Orthotopic cancer models, Pancreatic cancer, prostate cancer, small cell cancer, small cell lung cancer, small cell prostate cancer

Category(s): Medical Devices, Medical Devices > Neural Stimulation, Chemical, Electrical, Therapeutics, Therapeutics > Oncology

Programmable Micro-Mirrors for Real-Time Emissivity Control and Switching (Case No. 2025-254)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a fast-switching, MEMS-based thermal metasurface that enables real-time infrared emissivity modulation via high-contrast, broadband radiative control. Background: Dynamic emissive thermal devices offer active control over infrared (IR) radiation....

Published: 8/20/2025 | Inventor(s): Artur Davoyan, Mozakkar Hossain, Pavel Shafirin, Hanseong Jo, Tom Joly-Jehenne

Keywords(s): advanced thermal control materials, compact IR shielding, Dynamic thermal emissivity, EV battery cooling, Fluid Dynamics, heat control, heat controlling devices, Heat Transfer, infrared modulation, infrared signature suppression, IR camouflage, MEMS, MEMS metasurface, micro-electromechanical systems (MEMS), rapid emissivity modulation, real-time thermal management, stealth, thermal circuit, thermal conductance, thermal control, thermal control materials, Thermal Energy Storage, thermal metamaterials, thermal stability, thermal transistor, tunable radiative properties

Category(s): Electrical, Electrical > Electronics & Semiconductors

Multilevel Buffered Link (Case No. 2025-284)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel on-chip link that enhances communication performance and energy efficiency in modern integrated circuits. Background: On-chip communication enables data transfer between microchip components and is critical in computing, automotive, and industrial...

Published: 8/20/2025 | Inventor(s): Sudhakar Pamarti, Chih-Kong Yang, Haris Suhail

Keywords(s): Bandwidth (Signal Processing), buffer layer, Clock Signal, efficiency bandwidth products, Electrical, Electrical Engineering, Energy Efficiency, energy efficient IoT, energy-efficient, high-data-rate links, high-speed communications, IoT communication, large bandwidth, low-power device, Network On A Chip, scalable communication, scalable fabrication, Signaling pathways, Signal-To-Noise Ratio, System On A Chip

Category(s): Electrical, Electrical > Electronics & Semiconductors > Circuits, Electrical > Computing Hardware, Software & Algorithms > Communication & Networking, Electrical > Signal Processing

INSPIROMARK (Case No. 2025-293)

Summary: UCLA researchers have developed InspiroMark, a standardized, implantable imaging marker designed to enhance the efficiency, reliability and ease of grafted vessel localization following coronary artery bypass graft (CABG). Background: Coronary Artery Bypass Graft (CABG) surgery is a common procedure used to restore blood flow to the heart....

Published: 8/20/2025 | Inventor(s): Sneha Shaha, Michael Malig, Sukhneet Dhillon

Keywords(s):

Category(s): Diagnostic Markers, Medical Devices, Medical Devices > Cardiac, Medical Devices > Medical Imaging > CT, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging > X-Ray, Medical Devices > Medical Imaging > Fluorescence, Medical Devices > Monitoring And Recording Systems, Medical Devices > Surgical Tools, Therapeutics > Cardiovascular, Therapeutics > Radiology, Therapeutics > Transplant

Method and Apparatus for Segmentation of Dense MR Images Using Deep Learning with Domain Adaptation (Case No. 2025-208)

Summary: UCLA researchers from the Department of Radiological Sciences have developed a deep learning-based segmentation framework that enables fully automated and reproducible analysis of left ventricular (LV) function in Displacement Encoding with Stimulated Echoes (DENSE) MRI. Background: Myocardial strain is a key metric for analyzing how much...

Published: 8/18/2025 | Inventor(s): Xiaodong Zhong, Siyue Li, Kim-Lien Nguyen

Keywords(s): acute myocardial infarction, adjustable mount, aneurysm drainage, automatic leveling, bedside decisions, blood pressure monitoring, cardiac cycle, Cardiac Electrophysiology, Cardiac failure, Cardiac Magnetic Resonance Imaging, Cardiac MRI, Cardiovascular, Cardiovascular Disease, Cardiovascular Disease Nephropathy, cardiovascular diseases, cardiovascular monitoring, cerebrospinal fluid (CSF) drainage, Cine MRI, clamp, critical-care, CSF drainage, Deep learning MRI, DENSE MRI, laser alignment, Left ventricular segmentation, lumbar drains, Motion analysis, MRI, multiparametric MRI (mpMRI), Myocardial strain, non-invasive cardiac monitoring, operator variability, passive reflective target, phlebostatic axis measurement, Pseudo-labeling, radial MRI, Segment Anything Model (SAM), self-leveling system, transducer alignment, Unsupervised domain adaptation (UDA)

Category(s): Medical Devices > Cardiac, Electrical > Imaging, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Therapeutics > Cardiovascular, Therapeutics > Radiology, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging

A Compact Alignment Tool for Accurate Hemodynamic Monitoring: CardioAxis (Case No. 2025-294)

Summary: UCLA Biodesign researchers have created a laser-powered, self-leveling device that enables precise intracranial pressure monitoring and accurate phlebostatic axis measurement for hemodynamic monitoring. Background: Hemodynamic monitoring is crucial for measuring the delivery of blood and oxygen throughout the body and provides invaluable...

Published: 8/15/2025 | Inventor(s): Sneha Shaha, Michael Malig, Sukhneet Dhillon

Keywords(s): adjustable mount, aneurysm drainage, arterial blood pressure (ABP), automatic leveling, bedside decisions, blood flow management, Blood Pressure, blood pressure monitoring, central venous pressure (CVP), cerebrospinal fluid (CSF) drainage, clamp, Continuous blood pressure monitoring, critical-care, CSF drainage, hemodynamic monitoring, Hemodynamics, intracranial pressure, laser alignment, lumbar drains, operator variability, passive reflective target, phlebostatic axis measurement, pressure sensitive, pulmonary arterial pressure (PAP), self-leveling system, transducer alignment

Category(s): Medical Devices, Medical Devices > Hospital Systems, Medical Devices > Surgical Tools

Inhalational Therapy for Tuberculosis and Mycobacterial Lung Disease (UCLA Case No. 2025-278)

UCLA researchers from the Department of Medicine have identified drug combinations that can speed up treatment of tuberculosis by being delivered intranasally as well as orally. BACKGROUND: Tuberculosis (TB) is an airborne disease caused by the bacterium Mycobacterium tuberculosis, affecting more than 10 million people worldwide each year. The standard...

Published: 8/13/2025 | Inventor(s): Marcus Horwitz, Bai Yu Clemens, Daniel Clemens

Keywords(s):

Category(s): Platforms > Drug Delivery, Therapeutics > Infectious Diseases, Therapeutics > Respiratory And Pulmonary

Targeting the SV2 Family of Proteins for Immune Regulation (UCLA Case No. 2021-122)

UCLA researchers in the Department of Medicine have identified the SV2 family of proteins as novel druggable targets for suppressing severe inflammation, including COVID-19 pneumonia. Background: In critical COVID-19, the infection causes severe inflammation and excess fluid in the lungs, leading to breathing difficulties (COVID-19 pneumonia). Recent...

Published: 8/13/2025 | Inventor(s): Ke Shuai

Keywords(s):

Category(s): Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Respiratory And Pulmonary

Refractive Index-Corrected Light-Sheet Microscopy (Case No. 2025-176)

Summary: UCLA researchers from the Department of Medicine have developed a novel light-sheet fluorescence microscopy system that enables adaptive imaging across a range of refractive indices for enhanced biomedical imaging. Background: Light-sheet fluorescence microscopy (LSFM) has revolutionized biomedical imaging by allowing rapid and high-resolution...

Published: 8/15/2025 | Inventor(s): Tzung Hsiai, Enbo Zhu

Keywords(s): bioimaging, cell imaging, Fluorescence, fluorescence lifetime, Fluorescence Microscope, fluorescence microscopy, Fluorescence-Lifetime Imaging Microscopy Leading Lights, Fluorescent Labelling, Hyperspectral Imaging, immunofluorescence, Microscope, Microscopy, Microscopy And Imaging, Near-Field Scanning Optical Microscope

Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > Fluorescence, Optics & Photonics, Optics & Photonics > Microscopy, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging

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