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Engineered Gamma Delta T-Cells and Methods of Making and Using Thereof (UCLA Case No. 2020-913)

UCLA researchers in the Department of Molecular Immunology & Molecular Genetics have developed gamma delta (gd) T cell receptor gene-modified immune cells derived from stem and progenitor cells that enable scalable, off-the-shelf allogeneic cell therapies with broad therapeutic potential. BACKGROUND: Cell-based immunotherapies have demonstrated...

Published: 3/4/2026 | Inventor(s): Lili Yang, Derek Lee, Tyler Halladay

Keywords(s):

Category(s): Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Life Science Research Tools > Cell Lines, Therapeutics > Oncology, Therapeutics > CNS and Neurology, Therapeutics > Hematology, Therapeutics > Autoimmune, Therapeutics > Gene Therapy And Editing, Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Infectious Diseases

Engineered Models of Human Embryo Implantation - Microfabricated Cell Culture Platforms to Increase the Efficiency and Timing of Blastoid Formation and their Lineage Representation (UCLA Case No. 2026-096)

Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.

Published: 3/4/2026 | Inventor(s): Steven Jonas

Keywords(s):

Category(s): Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Women's Health

Novel Safe Potent Precisely Attenuated Mycobacterium Tuberculosis Vaccine Against Tuberculosis (UCLA Case No. 2026-109)

Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.

Published: 3/4/2026 | Inventor(s): Marcus Horwitz

Keywords(s):

Category(s): Therapeutics > Infectious Diseases

Gene-Modified Conventional Type 1 Dendritic Cells (UCLA Case No. 2026-093)

Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.

Published: 3/4/2026 | Inventor(s): Steven Dubinett

Keywords(s):

Category(s): Therapeutics > Immunology And Immunotherapy

Microbial Regulation of Immune Tolerance and Risk for Cancer (UCLA Case No. 2026-153)

Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.

Published: 3/4/2026 | Inventor(s): Elaine Hsiao

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

TCR-Dependent Exhaustion Signature and Blockade of HNF1B to Overcome T Cell Exhaustion for Cancer Immunotherapy (UCLA Case No. 2026-249)

Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.

Published: 3/4/2026 | Inventor(s): Cristina Puig Saus

Keywords(s):

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy

Transient Transcription Factor Reprogramming to Rejuvenate Exhausted Tumor-Specific T Cells Into Stem-Like Memory T Cells (UCLA Case No. 2024-240)

Details available soon. Please contact UCLA Technology Development Group if you have any questions or would like more information in the meantime.

Published: 3/4/2026 | Inventor(s): Tyler McCaw

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

Non-Destructive Probes for Known Good Die and Assembly Testing (Case No. 2026-073)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a liquid-metal-based, nondestructive probing platform for high-density semiconductor die and assembly testing. Background: As semiconductor devices become smaller and more complex, manufacturers face growing challenges in testing chips before they are...

Published: 3/2/2026 | Inventor(s): Subramanian Iyer, Samuel Wang

Keywords(s): biocompatible, Chipset, dielet assembly, Electrical, Electrical Engineering, Electronic Packaging, electronics packaging, high throughput testing, Liquid metal particles, liquid metals, low-cost fabrication, MEMS, micro-electromechanical systems (MEMS), Microelectronics Semiconductor Device Fabrication, scalable fabrication, Semiconductor, Semiconductor Device Fabrication, Semiconductors, soft electrical circuits, wafer-scale

Category(s): Electrical, Electrical > Electronics & Semiconductors, Materials, Materials > Fabrication Technologies, Materials > Semiconducting Materials, Mechanical > Manufacturing, Mechanical > Micro-Electromechanical Systems (Mems)

DNA Methylation Biomarkers to Predict Chronic Lung Allograft Dysfunction (UCLA Case No. 2025-9A0)

UCLA researchers in the Department of Medicine have developed a logistic regression model using DNA methylation biomarkers that enables early, noninvasive prediction of chronic lung allograft dysfunction up to two years before clinical disease onset. BACKGROUND: Chronic lung allograft dysfunction (CLAD) is the leading cause of long-term graft failure...

Published: 2/25/2026 | Inventor(s): Joanna Schaenman

Keywords(s):

Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Therapeutics > Respiratory And Pulmonary, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Bioinformatics, Software & Algorithms > Statistical Models

Superconducting Diodes for Qubit Readout (Case No. 2026-079)

Summary: UCLA researchers led by Professor Pri Narang have developed a fully superconducting, on-chip readout architecture that improves signal fidelity and limits backpropagation in quantum processors Background: Superconducting quantum processors can perform complex calculations orders of magnitude quicker than classical computers. Current superconducting...

Published: 3/3/2026 | Inventor(s): Prineha Narang, Arpit Arora, Nicolas Dirnegger

Keywords(s):

Category(s): Electrical, Electrical > Quantum Computing, Electrical > Signal Processing, Electrical > Sensors, Electrical > Instrumentation, Electrical > Computing Hardware, Materials, Materials > Fabrication Technologies, Materials > Functional Materials, Materials > Semiconducting Materials

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