Search Results - pei-yu+chiou

13 Results

Sort By:

Pulsed Laser Triggered High Speed Microfluidic Switch and Applications in Flourescent Activated Cell Sorting (Case No. 2009-063)

Summary UCLA researchers have developed a pulsed-laser triggered microfluidic switching mechanism capable of sub-100 µs switching (e.g. ~70 µs), enabling ultrafast cell/particle sorting in a microfluidic fluorescence-activated cell sorting (µFACS) platform using cavitation bubbles rather than mechanical valves. Background Flow cytometry...

Published: 9/25/2025 | Inventor(s): Pei-Yu Chiou, Ting Hsiang Wu

Keywords(s):

Category(s): Optics & Photonics, Optics & Photonics > Lasers, Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods

Continuous Whole-Chip 3-Dimensional Dep Cell Sorter and Its Fabrication (Case No. 2012-612)

Summary Researchers at UCLA have developed a continuous, whole-chip, three-dimensional dielectrophoretic (DEP) cell sorting device, integrating multi-layer microfluidics and electrode geometries to sort cells or particles throughout the thickness of a microfluidic chip, not merely at a single plane. Background Microfluidic cell sorting is vital in...

Published: 9/24/2025 | Inventor(s): Pei-Yu Chiou, Yu Jui Fan, Yu Chun Kung, Kuo Wei Huang

Keywords(s):

Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Optics & Photonics, Optics & Photonics > Microscopy, Electrical, Electrical > Imaging

Pulse Laser Driven High Speed, On-Demand, and Multiplexed Droplet Generator (Case No. 2013-184)

Summary UCLA researchers have developed a high-speed, on-demand microfluidic droplet platform that allows rapid and precise generation, manipulation, and merging of microdroplets for advanced lab-on-a-chip applications. The technology enables controlled droplet initiation and synchronized merging at high throughput, making it a versatile platform for...

Published: 9/24/2025 | Inventor(s): Pei-Yu Chiou, Michael Teitell, Ting Hsiang Wu, Yue Chen, Yu Chun Kung

Keywords(s):

Category(s): Optics & Photonics, Optics & Photonics > Lasers, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Research Methods, Life Science Research Tools > Cell Counting And Imaging

A Fabrication Method for High-Precision, Large-Area Acoustic Single-Cell Trapping Devices (Case No. 2025-115)

Summary: UCLA researchers from the Department of Mechanical and Aerospace Engineering have developed a novel fabrication method for single-cell trapping devices. Background: Single-cell analysis is critical to personalized medicine, diagnostics, and biomedical research, as it allows researchers to identify, isolate, and expand desired cell subpopulations....

Published: 8/8/2025 | Inventor(s): Pei-Yu Chiou, Jacob Smith

Keywords(s): acoustic manipulation, acoustics, air cavity formation, cell sorting, compliant membrane acoustic patterning (CMAP), Diagnostic Platform Technologies (E.G. Microfluidics), Digital Microfluidics, high-throughput analysis, large-area arrays, MEMS, Microfluidics, Microfluidics And Mem's, Microfluidics Dielectrophoresis, Microfluidics Multi-Band Device, Microfluidics Nanosphere, near-infrared (NIR) pulsed laser, PDMS, PDMS membranes, single cell analysis, Single cell data, single-cell resolution, single-cell trapping

Category(s): Materials, Materials > Membranes, Life Science Research Tools, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Cell Counting And Imaging, Platforms

High-Throughput Cargo Delivery Into Live Cells Using Photothermal Platforms (Case No. 2013-158)

Summary: UCLA researchers in the Department of Mechanical Engineering have developed a photothermal platform for precisely opening a cell membrane to deliver cargo into cells. Title: High-Throughput Cargo Delivery Into Live Cells Using Photothermal Platforms Background: Transferring cargo like proteins, nucleotides and particles into cells is valuable...

Published: 7/17/2025 | Inventor(s): Pei-Yu Chiou, Michael Teitell, Ting Hsiang Wu, Yi-Chien Wu

Keywords(s): cell engineering, cellular, delivery system, Gene delivery, Laser, Microbiology, Micropump

Category(s): Electrical > Mems, Life Science Research Tools > Microfluidics And Mems

Label-Free Optical Mapping for Large-Area Biomechanical Dynamics of Multicellular Systems (Case No. 2023-290)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel label-free optical mapping method for profiling real-time biomechanical dynamics over larger areas with high spatiotemporal resolution. Background: Mapping biomechanical dynamics often involves the use of various advanced technologies to measure...

Published: 2/14/2025 | Inventor(s): Pei-Yu Chiou, Yen-Ju Lin

Keywords(s): bioimaging, Biomechanics, cell imaging, Confocal Microscopy, dye, Fluorescence Microscope, labeling, Microscopy, Microscopy And Imaging, resolution, traction force microscopy

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Cell Counting And Imaging, Medical Devices, Medical Devices > Medical Imaging, Platforms, Platforms > Diagnostic Platform Technologies

2020-908 LASER ACTUATED SUPERCRITICAL INJECTOR (LASI)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering developed a platform that applies high-speed fluidic jet injection of biomolecules into biological samples with the use of laser actuated supercritical injector (LASI). Background: Intracellular delivery of various biomolecules has been of great importance in biomedical...

Published: 7/17/2025 | Inventor(s): Pei-Yu Chiou

Keywords(s):

Category(s): Life Science Research Tools > Microfluidics And Mems, Platforms > Drug Delivery, Optics & Photonics, Materials > Nanotechnology

Mechanisms and Devices Enabling Arbitrarily Shaped, Deep-Subwavelength, Acoustic Patterning

UC Case No. 2019-852SUMMARY:UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a Compliant Membrane Acoustic Patterning (CAMP) technology capable of patterning cells in an arbitrary pattern at a high resolution over a large area. BACKGROUND:Acoustic force has been investigated as a noninvasive, label-free, and...

Published: 7/17/2025 | Inventor(s): Pei-Yu Chiou, Kuan-Wen Tung, Benjamin Wu

Keywords(s): Cell Counting/Imaging, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Life Science Research Tools, Medical Devices and Materials, Microfluidics And Mem's, Monitoring And Recording Systems

Category(s): Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microfluidics And Mems, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies

Liquid Metal Enabled Multifunctional Neural Probes with Ultra-Large Tunable Stiffness

UC Case No. 2019-327SUMMARY: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel multifunctional neural probe with ultra-large tunable stiffness for electrochemical sensing and chemical delivery in the brain. BACKGROUND: Measuring brain activity has enormous applications including disease diagnosis...

Published: 7/17/2025 | Inventor(s): Pei-Yu Chiou, Ximiao Wen, Nigel Maidment, Brian Bo Wang

Keywords(s): Medical Devices and Materials

Category(s): Medical Devices > Monitoring And Recording Systems

2016-044 Plasmonic Nanoparticle Embedded PDMS Micropillar Array and Fabrication Approaches for Large Area Cell Force Sensing

Plasmonic Nanoparticle Embedded PDMS Micropillar Array and Fabrication Approaches for Large Area Cell Force SensingSUMMARYUCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel cell force sensor platform with high accuracy over large areas.BACKGROUNDMicrofabricated elastic pillar substrates with various geometries...

Published: 7/17/2025 | Inventor(s): Fan Xiao, Pei-Yu Chiou

Keywords(s): Electronics & Semiconductors, Life Science Research Tools, Microscopy And Imaging, Photonics

Category(s): Electrical > Electronics & Semiconductors, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Materials > Fabrication Technologies, Optics & Photonics

1 2