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2019-694 ROLE OF BACTERIAL RNA IN INFLAMMATION IN ACNE
SUMMARY:UCLA researchers in the Department of Dermatology have developed a new treatment for acne that can effectively alleviate the inflammatory response caused by acne-inducing bacteria. BACKGROUND:Acne is a chronic skin disease that was estimated to affect 633 million people globally in 2015, ranking as the 8th most common disease in the world....
Published: 7/19/2023
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Inventor(s):
Robert Modlin
Keywords(s):
Category(s):
Therapeutics > Dermatology
,
Therapeutics > Autoimmune
,
Therapeutics > Inflammation And Inflammatory Diseases
2012-340 A Novel Basic Fibroblast Growth Factor Conjugate for Broad Therapeutic Application
A Novel Basic Fibroblast Growth Factor Conjugate for Broad Therapeutic ApplicationSUMMARYUCLA scientists have developed a novel polymer conjugate of basic fibroblast growth factor (bFGF) for use in commercial and possibly clinical applications. This is the first bFGF conjugate to enhance bioactivity and stability under environmental stressors. BACKGROUNDBasic...
Published: 7/19/2023
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Inventor(s):
Heather Maynard
,
Thi Nguyen
Keywords(s):
Catalysts
,
Dermatology
,
Other Polymers
,
Therapeutics & Vaccines
Category(s):
Chemical > Synthesis
,
Therapeutics
,
Therapeutics > Dermatology
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Platforms > Drug Delivery > Other Polymers
2004-087 Antimicrobial Peptide for the Treatment of Skin Diseases
Antimicrobial Peptide for the Treatment of Skin DiseasesSUMMARYGranulysin peptides are small antimicrobial agents with potent activity against bacteria and inflammation. A pharmaceutical composition comprising granulysin peptides as an active agent is administered therapeutically to a patient suffering from a microbial infection.
Published: 7/19/2023
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Inventor(s):
David Eisenberg
,
Robert Modlin
,
Jenny Kim
,
Daniel Anderson
,
Richard Gallo
Keywords(s):
Dermatology
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics > Dermatology
2010-243 Application of Topical Resveratrol in the Treatment of Acne
Application of Topical Resveratrol in the Treatment of AcneSUMMARYResearchers in UCLA Department of Dermatology have demonstrated through in vitro experiments that resveratrol, an ingredient in antioxidants and anti-aging products, generates sustained bactericidal and anti-inflammatory effects against P. acnes, the bacteria involved in the pathogenesis...
Published: 7/19/2023
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Inventor(s):
Emma Taylor
,
Jenny Kim
,
Jackson Champer
Keywords(s):
Agbio
,
Dermatology
,
Nutraceuticals / Probiotics
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics > Dermatology
,
Therapeutics > Agtech And Animal Health
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Therapeutics > Nutraceuticals And Probiotics
2012-063 A MULTIPLEX PCR-BASED TESTING FOR PSEUDOEPITHELIOMATEOUS HYPERPLASIA AND SQUAMOUS CELL CARCINOMA OF THE SKIN
Diagnostic Markers to Distinguish Between Squamous Cell Carcinoma and Pseudoepitheliomatous HyperplasiaSUMMARYUCLA scientists have developed a novel diagnostic kit to reliably distinguish squamous cell carcinoma (SCC) from pseudoepitheliomatous hyperplasia (PEH). This fast diagnostic test can replace the non-quantitative and subjective diagnostic methods...
Published: 7/19/2023
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Inventor(s):
Xinmin Li
,
Scott Binder
,
Jian Zhao
,
Seong Ra
Keywords(s):
Dermatology
,
Diagnostic Markers & Platforms
,
Oncology
Category(s):
Diagnostic Markers
,
Therapeutics > Dermatology
,
Therapeutics > Oncology
2011-788 Use of ApoA-1 to Treat and Prevent Pro-Inflammatory Conditions
UCLA researchers in the Department of Obstetrics and Gynecology have discovered that ApoA-I can be used to treat and prevent pro-inflammatory skin conditions.BACKGROUNDInflammation is a standard immune signaling process that is strongly associated with stress and is connected to various diseases. Inflammation is activated to fight infection or invasion...
Published: 7/19/2023
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Inventor(s):
Srinivasa Reddy
,
Robin Farias-Eisner
Keywords(s):
Autoimmune
,
Dermatology
,
Inflammatory Diseases
,
Oncology
,
Oncology (Small Molecules, Peptides and Antibodies)
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics > Autoimmune
,
Therapeutics > Dermatology
,
Therapeutics > Oncology
,
Therapeutics > Inflammation And Inflammatory Diseases
,
Therapeutics > Oncology > Oncology (Small Molecules)