Search Results - therapeutics+%3e+orthopaedics

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Bone Depth Gauge Design and Deployable Mechanism (Case No. 2024-185)

Summary: Researchers in the Department of Head and Neck Surgery at UCLA have developed a novel bone depth gauge and deployable mechanism for orthopaedic screw insertion. Background: Orthopaedic screws are typically used in surgeries to treat fractures that may have been caused intentionally, such as for tumor resection or joint replacement, or...

Published: 3/24/2025 | Inventor(s): Ashley Kita, Eric Smith, Rhorie Kerr

Keywords(s): bone health, Invasiveness Of Surgical Procedures, Orthopaedics, Orthopedics and Prosthetics (O & P), Surgical Instrument, surgical tool

Category(s): Diagnostic Markers > Aging, Mechanical > Sensors, Medical Devices, Medical Devices > Surgical Tools, Therapeutics > Orthopaedics, Therapeutics > Musculoskeletal Disease, Therapeutics > Inflammation And Inflammatory Diseases

Metamorphic Hybrid Compliant Mechanisms (Case No. 2025-038)

Summary: Researchers in the Mechanical Engineering Department at UCLA have developed a compliant technique that can be utilized for a wide array of industries, including next-generation joint reconstruction surgeries, precision manufacturing, robotics, aerospace transportation, and automation applications. Background: Bearings are commonly used to...

Published: 3/13/2025 | Inventor(s): Tyler Clites, Cameron Taylor, He Kai Lim, Jonathan Hopkins

Keywords(s): Aeronautics, Aerospace Engineering, Automation, biomedical implantation, compliant mechanisms, constraint design, Energy Efficiency, flexure systems, Implant (Medicine), multi-degrees of freedom (DOF), Orthopaedics, Orthopedics and Prosthetics (O & P), Robotics

Category(s): Mechanical > Aeronautics & Aerospace, Mechanical > Robotics, Mechanical > Manufacturing, Mechanical > Instrumentation, Mechanical > Mechanical Systems, Medical Devices > Prosthetics, Medical Devices > Surgical Tools, Therapeutics > Orthopaedics, Materials, Therapeutics > Musculoskeletal Disease

Control of Periprosthetic Joint Infections (Case No. 2021-334)

Summary: UCLA researchers in the Department of Orthopaedic Surgery have developed a non-invasive method to disrupt biofilms on orthopaedic implants and decrease the overall rate of infections. Background: Prosthetic joint infection (PJI) remains a serious complication in hip and knee arthroplasty, with skyrocketing revision rates across all orthopaedic...

Published: 2/14/2025 | Inventor(s): Fabrizio Billi, Beth Lazazzera

Keywords(s): Biofilm, Cell Growth, electromagnetic, Infection, Nanoparticle, Orthopaedics, Orthopedics and Prosthetics (O & P), Osteo, Prosthetics

Category(s): Medical Devices > Prosthetics, Chemical > Coatings, Adhesives & Inks, Diagnostic Markers > Immunology, Materials > Membranes, Medical Devices > Coatings, Therapeutics > Orthopaedics

2022-014 Prevention of Bone Loss With Probiotic Bacteria AJ2 and/or Super-Charged NK Cells in Cancer and Other Diseases

SUMMARY: UCLA researchers in the School of Dentistry have discovered novel therapeutic methods involving probiotic bacteria and super-charged natural killer cells that successfully prevent bone loss in pancreatic cancer, with huge therapeutic potential for other cancer types and diseases. BACKGROUND: Metabolic bone disorders are associated with several...

Published: 2/14/2025 | Inventor(s): Anahid Jewett

Keywords(s):

Category(s): Therapeutics, Therapeutics > Oncology, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Orthopaedics

2019-252 Spinopelvic Mobility Sensor Guided Hip Arthroplasty Navigation System

SUMMARY:UCLA researchers from the Department of Orthopedic Surgery have developed sensors to assist surgeons in finding the ideal angle for a hip replacement. BACKGROUND:To reduce dislocation rates after hip surgery, understanding the spinopelvic motion (or how much the pelvis moves or “rolls back”) when a patient goes from a standing to...

Published: 2/14/2025 | Inventor(s):

Keywords(s): Orthopaedics, Surgical Tools

Category(s): Medical Devices > Surgical Tools, Therapeutics > Orthopaedics

2017-723 An Osteoadsorptive Fluorogenic Substrate of Cathepsin K for Imaging Osteoclast Activity and Migration

An Osteoadsorptive Fluorogenic Substrate of Cathepsin K for Imaging Osteoclast Activity and MigrationSUMMARYUCLA researchers in the Department of Dentistry have developed a novel fluorescent probe for studying the role of osteoclasts in bone diseases and for detecting the early onset of bone resorption by targeting an important protein Cathepsin K....

Published: 2/14/2025 | Inventor(s): Ichiro Nishimura, Akishige Hokugo, Charles Mckenna, Eric Richard, Boris Kashemirov, Kenzo Morinaga

Keywords(s): Animal Imaging, Autoimmune, Diagnostic Markers & Platforms, Drug Delivery, Fluorescence, Life Science Research Tools, Medical Imaging, Orthopaedics

Category(s): Life Science Research Tools > Animal Imaging, Life Science Research Tools, Diagnostic Markers, Medical Devices > Medical Imaging, Platforms > Drug Delivery, Therapeutics > Autoimmune, Medical Devices > Medical Imaging > Fluorescence, Therapeutics > Orthopaedics

2009-254 Functionalized Titanium Implants and Related Regenerative Materials

Functionalized Titanium Implants And Related Regenerative MaterialsSUMMARYUCLA researchers in the Department of Dentistry have developed novel titanium surfaces with enhanced bioactivity in implants and tissue regeneration.BACKGROUNDTitanium implants are widely used in the over 500,000 hip and knee reconstruction procedures performed annually in the...

Published: 2/14/2025 | Inventor(s): Takahiro Ogawa

Keywords(s): Dental, General Device Coatings, Medical Devices and Materials, Orthopaedics

Category(s): Medical Devices, Medical Devices > Coatings, Therapeutics > Orthopaedics, Therapeutics > Dental