Search Results - endocrinology

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2017-502 Novel Targets and Use of Small Molecule BT-2 to Treat Heart Failure, Obesity and Diabetes

Novel Targets And Use Of Small Molecule BT-2 To Treat Heart Failure, Obesity And DiabetesSUMMARYUCLA researchers from the Cardiovascular Theme in the Departments of Anesthesiology, Physiology and Medicine have discovered new pathways and potential treatment options for heart failure, obesity, and diabetesBACKGROUNDHeart failure is a leading cause of...

Published: 7/19/2023 | Inventor(s): Yibin Wang, Haipeng Sun

Keywords(s): Cardiovascular, Endocrinology, Metabolic Diseases

Category(s): Therapeutics > Cardiovascular, Therapeutics > Metabolism And Endocrinology

A Wearable Platform for In-Situ Analysis of Hormones

UC Case No. 2018-657SUMMARY:UCLA researchers in the Department of Electrical and Computer Engineering have developed a highly sensitive, wearable hormone monitoring platform.BACKGROUND:Biofluid levels provide insight for monitoring depression, reproduction, and stress. Invasive methods are used to detect low-concentration biofluids. However, realizing...

Published: 7/19/2023 | Inventor(s): Sam Emaminejad, Sanaz Pilehvar

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Endocrinology, Gastroenterology & Digestive Disease, Life Science Research Tools, Medical Devices and Materials, Psychiatry / Mental Health

Category(s): Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology, Therapeutics > Psychiatry And Mental Health

2013-076 Improved Treatment of Acute Metabolic Acidosis

Improved Treatment of Acute Metabolic AcidosisSUMMARYProfessors Thomas Mason and Jeffrey Kraut in UCLA’s Department of Chemistry and School of Medicine, respectively, have developed improved materials and methods of treating acute metabolic acidosis.BACKGROUNDMetabolic acidosis is a condition in which blood pH becomes abnormally acidic. It can...

Published: 7/19/2023 | Inventor(s): Thomas Mason, Jeffrey Kraut

Keywords(s): Endocrinology, Metabolic Diseases, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Metabolism And Endocrinology

2019-463 PREVENTION OF THE LATE COMPLICATIONS OF ACUTE PANCREATITIS

SummaryUCLA researchers in the Department of Medicine and Surgery have developed a novel therapeutic for the prevention of late inflammatory complications in severe acute pancreatitis patients.BackgroundAcute pancreatitis, or sudden inflammation of the pancreas, a disease generally caused by gallstones or alcohol abuse, is a common reason for hospitalization...

Published: 7/19/2023 | Inventor(s): Jonathan Kaunitz, Yasutada Akiba

Keywords(s): Endocrinology, Gastroenterology & Digestive Disease, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology

2013-369 METHOD TO DIRECT THE RECIPROCAL INTERACTIONS BETWEEN THE URETERIC BUD AND THE METANEPHRIC MESENCHYME

Method to Direct the Reciprocal Interactions Between the Ureteric Bud and the Metanephric MesenchymeSUMMARYResearchers at UCLA have developed an approach to construct an embryonic kidney in vitro for the treatment of end stage renal disease.BACKGROUNDEnd stage renal disease (ESRD) is a fatal illness characterized by the permanent loss of kidney function...

Published: 9/20/2023 | Inventor(s): Peter Hauser, Norimoto Yanagawa, Masaki Nishikawa, Morgan Hamon

Keywords(s): Endocrinology, Gene Editing Systems, Gene Therapy, iPS/stem cells, Life Science Research Tools, Medical Devices and Materials, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Medical Devices, Therapeutics, Therapeutics > Gene Therapy And Editing, Therapeutics > Metabolism And Endocrinology, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

2019-621 DRUG REPURPOSING TO EXPLORE NOVEL TREATMENT FOR CUSHING DISEASE

SummaryUCLA researchers in the Department of Medicine and the Department of Molecular and Medicinal Pharmacology have identified several small molecule reagents to treat Cushing disease.BackgroundCushing disease is a rare disease characterized by excessive adrenal-derived cortisol production, primarily as a result of adrenocorticotropic hormone (ACTH)-secreting...

Published: 7/19/2023 | Inventor(s): Anthony Heaney

Keywords(s): Endocrinology, Life Science Research Tools, Metabolic Diseases, Targets And Assays, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Diagnostic Markers > Targets And Assays, Therapeutics, Therapeutics > Metabolism And Endocrinology

Second-Generation Estrogen Receptor Down-Regulators for Medical Therapy

Case 2015-166UCLA researchers in the School of Medicine have developed a series of novel estrogen receptor antagonists for breast cancer therapy.BACKGROUNDBreast cancer is the most common malignancy in women in North America. Each year, more than 210,000 new cases of breast cancer are diagnosed in the US. About 70% of breast cancers depend on estrogen...

Published: 7/19/2023 | Inventor(s): Richard Pietras, Michael Jung

Keywords(s): Endocrinology, Oncology, Oncology (Small Molecules, Peptides and Antibodies), Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Oncology, Therapeutics > Metabolism And Endocrinology, Therapeutics > Oncology > Oncology (Small Molecules)