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Search Results - therapeutics+%3e+stem+cells+and+regenerative+medicine+%3e+ips+stem+cells
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2023-102 A Dynamic Cholesteric Liquid Crystal for Organoid, Spheroid, 3D Cell Aggregate Manufacturing
Summary: UCLA and University of Connecticut researchers have engineered a novel liquid-crystal-based biomaterial with a simple fabrication process for organoid, spheroid and 3D cell aggregate manufacturing that enables rapid cell growth. Background: The current waiting list for people who need a lifesaving organ transplant is over 100,000 cases...
Published: 7/19/2023
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Inventor(s):
Paul Weiss
,
Amir Nasajpour
,
Ali Tamayol
,
Mohamadmahdi Samandari
Keywords(s):
3D biofabrication
,
3D Printing
,
Biocompatibility
,
biocompatible
,
Biomaterial 3D Printing
,
biomedical implantation
,
Cell and tissue culture
,
Cell Culture
,
cell-extracellular matrix (ECM)
,
cellular aggregates
,
Cellular agriculture
,
Cholesterol
,
cholesteryl ester liquid crystals (CLCs)
,
Cultured meat
,
Electrode 3D Printing
,
liquid crystal
,
liquid crystal nanofibers
,
mesogens
,
Organ Transplant
,
organogenesis
,
scaffolds
,
self-assemble
,
Stem Cells / Regenerative Medicine
,
Tissue Engineering
Category(s):
Chemical
,
Chemical > Polymers
,
Materials
,
Materials > Functional Materials
,
Life Science Research Tools
,
Life Science Research Tools > Research Methods
,
Life Science Research Tools > Other Reagents
,
Medical Devices
,
Medical Devices > Surgical Tools
,
Therapeutics
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2021-182: COMBINING AUTOLOGOUS OR ALLOGENEIC TOTAL MONOCYTES OR CD16+ MONOCYTES TO PROTECT AND INCREASE THE EXPANSION AND FUNCTION OF STEM CELLS.
SUMMARY: UCLA researchers in the department of Dentistry have developed a novel approach to increase the successful transplantation and survival of stem cells into patients. BACKGROUND: The World Health Organization has recognized that transplantation of human cells saves and restores essential life functions to patients who are not presented with...
Published: 2/16/2024
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Inventor(s):
Anahid Jewett
Keywords(s):
Category(s):
Therapeutics
,
Therapeutics > CNS and Neurology
,
Therapeutics > Immunology And Immunotherapy
,
Therapeutics > Stem Cells And Regenerative Medicine
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2020-421 EXTRACELLULAR VESICLES DERIVED FROM INDUCED PLURIPOTENT STEM CELLS FOR IMMUNOMODULATION
UCLA researchers in the Department of Bioengineering have developed a method to boost extracellular vesicles' (EVs) production and potency, potentially allowing large-scale clinical-grade EV manufacture for immunomodulatory therapeutics. BACKGROUNDExtracellular vesicles (EVs) are one of the most important mediators of cell-to-cell communication. EVs...
Published: 7/19/2023
|
Inventor(s):
Jana Zarubova
,
Mohammad Hasani-Sadrabadi
,
Song Li
Keywords(s):
Immunology
,
Therapeutics & Vaccines
,
Transplant Rejection
Category(s):
Life Science Research Tools > Research Methods
,
Therapeutics > Agtech And Animal Health
,
Therapeutics > Inflammation And Inflammatory Diseases
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2019-870 GENE EDITING OF MONOGENIC DISORDERS IN HUMAN HEMATOPOIETIC STEM CELLS (XHIM)
Researchers at the UCLA Department of Microbiology, Immunology & Molecular Genetics have developed novel methods to achieve efficient, precise gene integration and effective expression of cDNA cassettes to express normal versions of genes in hematopoietic stem cells. BACKGROUND:Hematopoietic stem cells (HSCs)—stem cells that give rise to...
Published: 7/19/2023
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Inventor(s):
Donald Kohn
Keywords(s):
Gene Editing Systems
,
Gene Therapy
,
Genetic Disease
,
Hematology
,
Immunotherapy
,
iPS/stem cells
,
Therapeutics & Vaccines
,
Viral Delivery Systems
Category(s):
Therapeutics > Gene Therapy And Editing
,
Therapeutics > Hematology
,
Therapeutics > Immunology And Immunotherapy
,
Therapeutics > Stem Cells And Regenerative Medicine
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2020-443 A PATCH OF DETACHABLE HYBRID MICRONEEDLE DEPOT (D-HMND) FOR LOCALIZED DELIVERY OF MESENCHYMAL STEM CELLS IN REGENERATION THERAPY
UCLA researchers in the Department of Bioengineering have developed a novel detachable hybrid microneedle depot (d-HMND) for the targeted delivery of mesenchymal stem cells. BACKGROUND: Stem cell biology has been widely applied to the treatment of tissue damage, due to the ability of stem cells to form, repair, and maintain tissues and organs after...
Published: 7/19/2023
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Inventor(s):
Ali Khademhosseini
Keywords(s):
iPS/stem cells
,
Life Science Research Tools
,
Stem Cells / Regenerative Medicine
,
Therapeutics & Vaccines
Category(s):
Therapeutics > Stem Cells And Regenerative Medicine
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2017-657: Gene Editing Stem Cells for Generating Non-Alloreactive T Cells for Immunotherapy
SUMMARY UCLA researchers in the Department of Pathology and Medicine have developed human stem cells that can be used to generate non-alloreactive, antigen specific T cells for adoptive cell therapy. BACKGROUND Adoptive cell therapy (ACT) with engineered T cells has shown unprecedented potential in the treatment of cancer, infectious diseases,...
Published: 9/5/2023
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Inventor(s):
Gay Crooks
,
Christopher Seet
,
Amelie Montel Hagen
Keywords(s):
Gene Editing Systems
,
Gene Therapy
,
iPS/stem cells
,
Life Science Research Tools
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Therapeutics
,
Therapeutics > Gene Therapy And Editing
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2011-562 A Method for Manufacturing Potent Dendritic Cells
SummaryDendritic cells (DCs) are antigen-presenting cells that play a critical role in the regulation of adaptive immune responses. They instruct and activate T cells and are therefore crucial for establishing immunological memory. Immense research effort is being expended to create dendritic cell vaccines, which may potentially prime a patient's immune...
Published: 7/19/2023
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Inventor(s):
Keywords(s):
Category(s):
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
From Teeth to Hearing: A Promising Source of Stem Cells for Sensorineural Hearing Loss Treatment (Case No. 2020-135)
SUMMARY: UCLA researchers in the Department of Dentistry have identified a novel source of stem cells that selectively differentiate towards auditory progenitors under appropriate conditions, for the treatment of both acute and chronic sensorineural hearing loss. BACKGROUND: Hearing loss is the most prevalent sensory disability in humans....
Published: 9/26/2023
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Inventor(s):
Alireza Moshaverinia
,
Sevda Pouraghaei Sevari
Keywords(s):
Cns
,
iPS/stem cells
,
Life Science Research Tools
,
Medical Devices and Materials
,
Therapeutics & Vaccines
Category(s):
Therapeutics > CNS and Neurology
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2018-470 NOVEL SOURCES OF HEMATOPOIETIC PROGENITOR CELLS
Novel Sources of Hematopoietic Progenitor CellsTech ID: 30298 / UC Case 2018-470-0SUMMARYUCLA researchers in the Department of Urology have developed a novel method of collecting hematopoietic stem cells from deceased donors that preserves the donor body and organs for further donations.BACKGROUNDHematopoietic stem cell (HSC) transplantation is growing...
Published: 7/19/2023
|
Inventor(s):
Jeffrey Veale
,
Neil Kogut
,
Thomas Mone
Keywords(s):
Hematology
,
iPS/stem cells
,
Life Science Research Tools
Category(s):
Life Science Research Tools
,
Therapeutics > Hematology
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2004-084 Adipose Derived Stem Cells for Reconstruction of the Urinary Tract
Stem Cell Urinary Tract Reconstruction TherapySUMMARYResearchers from the UCLA Department of Urology have successfully harvested stem cells from adipose tissue and differentiate them into functioning smooth muscle cells. These adipose derived stem cells can then be used for reconstruction or tissue engineering of smooth muscle containing organs, especially...
Published: 7/19/2023
|
Inventor(s):
Benjamin Wu
,
Larissa Rodriguez
Keywords(s):
iPS/stem cells
,
Renal
,
Stem Cells / Regenerative Medicine
,
Urology
Category(s):
Therapeutics > Urology
,
Therapeutics > Renal
,
Therapeutics > Stem Cells And Regenerative Medicine
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
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