Search Results - diagnostic+markers+%3e+targets+and+assays

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Detection of Dicrotic Notch in Arterial Pressure and Photoplethysmography Signals Using Iterative Envelope Mean Filter (Case No. 2024-034)
Summary: UCLA Researchers in the Department of Anesthesiology have developed an iterative envelope mean (IEM) method for the detection of specific features in arterial pressure monitoring applications. Background: The cardiac cycle consists of the distinct systolic and diastolic phases. The transition from the contracted, systolic phase to the...
Published: 4/8/2024   |   Inventor(s): Maxime Cannesson, Ravi Pal, Akos Rudas, Jeffrey Chiang, Sungsoo Kim
Keywords(s): arrhythmia, arterial blood pressure (ABP), cardiac cycle, Cardiac Electrophysiology, Cardiac failure, Cardiac Magnetic Resonance Imaging, cardiometabolic disease, cardiopulmonary illness, Cardiovascular, Cardiovascular Disease, Cardiovascular Disease Nephropathy, cardiovascular modeling, cardiovascular prediction, cardiovascular therapeutic solution, diastolic, diastolic phase peak, dicrotic notch, feature extraction tool, iterative envelope method (IEM), Medical Device, medical device cardiac monitoring, Medical Device Poly(Methyl Methacrylate), Medical Devices and Materials, non-invasive cardiac monitoring, photoplethysmography (PPG), Smart medical device, systolic, tachycardia, wearable medical device, wearable medical devices
Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms, Platforms > Diagnostic Platform Technologies, Software & Algorithms, Diagnostic Markers > Targets And Assays, Diagnostic Markers
Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of biomarkers in bodily fluids....
Published: 4/1/2024   |   Inventor(s): Aydogan Ozcan, Hyou-Arm Joung, Hyun-June Jang, Junhong Chen
Keywords(s): Biomarker, biomarkers, Biomaterial, Biosensor, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Electrical, Electrical Engineering, electrically-mediated sensing, electrochemical sensors, enzyme functionalization, Medical diagnostics, multiplexed analysis, Point Of Care, point-of-care, porous media, sample matrix effects, transistors
Category(s): Electrical, Electrical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms, Platforms > Diagnostic Platform Technologies
Swabseq Agnostic Diagnostic Platform (Case No. 2023-293)
Summary: UCLA researchers in the Departments of Computer Science and Anatomic Pathology have developed an untargeted NGS diagnostic tool capable of detecting all known and emerging respiratory RNA viruses in a single test, enhancing our capacity to rapidly address public health crises through improved diagnostics. Background: Most clinical diagnostic...
Published: 11/29/2023   |   Inventor(s): Eleazar Eskin, Valerie Arboleda
Keywords(s): agnostic detection, Bioinformatics, bioinformatics pipeline, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Test, DNA Sequencing, Medical diagnostics, metagenomic diagnostic platform, meta-genomics, next generation sequencing (NGS), Pathogen, Pathogenesis, Sequencing
Category(s): Platforms, Platforms > Diagnostic Platform Technologies, Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Bioinformatics
Core-Shell Hydrogel Particles With Tunable Porosity for Digital Nucleic Acid Assays (Case No. 2023-058)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel method to perform ultra-high sensitivity, low-cost nucleic acid amplification assays utilizing porous microdroplets. Background: Nucleic acid concentration measurement is essential in biological research and diagnostics. The 2020 pandemic underscored the importance...
Published: 8/30/2023   |   Inventor(s): Dino Di Carlo, Michael Thomas Alesse Bogumil
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Flow Cytometry, Medical diagnostics
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Targets And Assays, Chemical > Emulsions, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies
Stain-Free, Rapid, and Quantitative Viral Plaque Assay Using Deep Learning and Holography (Case No. 2022-326)
Intro Sentence: UCLA researchers in the Department of Electrical and Computer Engineering have developed a rapid and stain-free quantitative assay using lens-free holography and deep learning to efficiently and cost-effectively determine the presence of viral plaque-forming units (PFUs) in samples. Background: A broad range of viruses have caused...
Published: 3/7/2024   |   Inventor(s): Aydogan Ozcan, Yuzhu Li, Tairan Liu
Keywords(s): Antiviral Drug, Artifical Intelligence (Machine Learning, Data Mining), Assay, Bioassay, Computer Aided Learning, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Digital Holography, Electrical, Electrical Brain Stimulation, Electrical Breakdown, Electrical Engineering, Electrical Impedance, Electrical Load, Electrical Load Equation Of State, Electrical Resistance And Conductance, Electrical Resistivity And Conductivity, Holography, Immunoassay, Immunoassay Sense (Molecular Biology), Lentivirus Viral Vector, Machine Learning, Machine Learning Autonomous Car Gradient Descent, Machine Learning Pain Management, Machine Learning Particulates Global Climate Model, Network Analysis (Electrical Circuits), Perceptual Learning, Plasmid Trabecular Meshwork Aqueous Humour Viral Vector, Targets And Assays, Transcutaneous Electrical Nerve Stimulation, Transfection Viral Vector, Unsupervised Learning , Viability Assay, Viral Delivery Systems, Viral Envelope, Viral Load
Category(s): Diagnostic Markers, Diagnostic Markers > Targets And Assays, Electrical, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Software & Algorithms > Artificial Intelligence & Machine Learning
2022-067 Multiwell Plate-Based Flow Culture for Improving the Quality of 3D Tissues
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a simple, innovative method for growing 3D cell cultures with improved organoid differentiation and reduced hypoxia-induced cell death. TITLE: Multiwell Plate-Based Flow Culture for Improving the Quality of 3D Tissues Background: 3D tissue culture,...
Published: 4/5/2024   |   Inventor(s): Neil Lin, Marie Payne
Keywords(s): 3D Printing, Biofilm, Biomaterial 3D Printing, Biomedical Engineering, Cancer, cancer detection, Cancer Immunotherapy, Cell and tissue culture, Cell Culture, Cellular agriculture, Cultured meat, iPS/stem cells, Laminar flow, Microwell plates, organogenesis, Organoids, Personalized Pharmacotherapy, Pharmaceutical testing, Stem Cells / Regenerative Medicine, Tissue (Biology), tissue detection, Tissue Engineering, Tissue sedimentation
Category(s): Life Science Research Tools > Lab Equipment, Life Science Research Tools, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Therapeutics, Therapeutics > Oncology
2014-9AG Wide-Field Computational Imaging of Pathology Slides Using Lensfree On-Chip Microscopy
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a wide field-of-view (FOV) computational imaging method using lens-free on-chip microscopy to efficiently and cost-effectively scan biological samples such as pathology slides. Background: Wide field-of-view (FOV) and high-resolution imaging is crucial...
Published: 7/19/2023   |   Inventor(s): Aydogan Ozcan, Alon Greenbaum, Yibo Zhang, Alborz Feizi, Wei Luo
Keywords(s): 4Pi Microscope, Adaptive Optics, Animal Imaging, Antenna (Radio) Flip Chip DisplayPort, Artificial Intelligence, Atomic Force Microscopy, Atomic Force Microscopy Insulator (Electricity), Atomic Force Microscopy Optical Tweezers, Bright Field Microscopy, Cardiac Magnetic Resonance Imaging, Cell Counting/Imaging, Chipset, Confocal Microscopy, Cytopathology, Dark Field Microscopy, Dispersion (Optics), Electron Microscope, Electro-Optics, Fluorescence Microscope, Fluorescence-Lifetime Imaging Microscopy Leading Lights, Focus (Optics), Functional Magnetic Resonance Imaging, Histopathology, Hyperspectral Imaging, Imaging, Infrared Electromagnetic Spectrum Dispersion (Optics), Lab-On-A-Chip, Lens (Optics), Magnetic Resonance Imaging, Magnetic Resonance Imaging Carotid Artery Stenosis, Magnetic Resonance Imaging Hypoxia (Medical), Magnetic Resonance Imaging Medical Physics, Magnetic Resonance Imaging Microangiopathy, Magnetic Resonance Imaging Pathology, Magnetic Resonance Imaging Spin Polarization, Magnetic Resonance Imaging Unmanned Aerial Vehicle, Medical Imaging, Medical Imaging Eyepiece, Microscale Chemistry, Microscope, Microscopy, Microscopy And Imaging, Molecular Imaging, Molecular Imaging Physics Of Magnetic Resonance Imaging, Molecular Imaging Ylide, Near-Field Scanning Optical Microscope, Network On A Chip, Neuroimaging, Neuropathology, Nonlinear Optics, Nonlinear Optics Molecular Dynamics, Optical Microscope, Optics, Optics Parabolic Reflector Curved Mirror, Phase-Contrast Imaging, Phase-Contrast Imaging Genomics, Prism (Optics), Scanning Probe Microscopy, Scanning Tunneling Microscope, Serial Time-Encoded Amplified Microscopy, STED Microscopy, Stereo Microscope, Super Resolution Microscopy, System On A Chip, Transmission Electron Microscopy
Category(s): Life Science Research Tools, Electrical, Electrical > Imaging, Life Science Research Tools > Microscopy And Imaging, Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Medical Devices > Medical Imaging
2019-044: Sodium-Dependent Glucose Transporter 2 as a Diagnostic and Therapeutic Target for Early-Stage Cancer
­SUMMARY: UCLA researchers in the Department of Medicine have developed a clinical screening method for early-stage lung cancer utilizing a newly discovered biomarker and subsequently shown that inhibitors of this biomarker result in cancer interception. BACKGROUND: The National Cancer Institute reports that lung cancer accounts for 28% of all...
Published: 9/5/2023   |   Inventor(s): Claudio Scafoglio, Steven Dubinett
Keywords(s):  
Category(s): Diagnostic Markers > Targets And Assays, Therapeutics > Oncology, Therapeutics > Respiratory And Pulmonary
2016-219-3 SYSTEM AND METHOD FOR OPTICAL TRANSIENT LIQUID MOLDING OF MICROPARTICLES AND USES FOR THE SAME
SUMMARY: The Di Carlo group at UCLA has invented a microparticle that enables analysis of adherent cells via flow cytometry with high throughput. BACKGROUND: Traditional flow cytometry is a fluorescence-based technique used to characterize cells on a molecular level usually suspended in a fluid. However, many cells are inherently attached to matrix...
Published: 7/19/2023   |   Inventor(s): Dino Di Carlo, Chueh-Yu Wu
Keywords(s): Cell Counting/Imaging, Cytometry, Diagnostic Platform Technologies (E.G. Microfluidics), Flow Cytometry, Life Science Research Tools, Microfluidics, Microfluidics And Mem's, Targets And Assays
Category(s): Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microfluidics And Mems, Platforms > Diagnostic Platform Technologies
2021-313 METHODS OF ANALYZING NANOVIALS CONTAINING CELLS USING FLUORESCENCE ACTIVATED CELL SORTING
Summary: UCLA researchers in the Department of Bioengineering have developed a high throughput, single cell screening and sorting platform to facilitate single cell functional assays. Background: Biological assays are usually performed using microwell plates because of their ability to scale experiments and integrate with current lab automation...
Published: 7/19/2023   |   Inventor(s): Dino Di Carlo, Joseph de Rutte, Robert Dimatteo
Keywords(s): Assay, Biotechnology, Life Science Research Tools, Nanotechnology, Targets And Assays
Category(s): Life Science Research Tools > Cell Lines, Life Science Research Tools > Research Methods, Materials > Functional Materials, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Cell Counting And Imaging, Materials > Nanotechnology
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