Search Results - life+science+research+tools+%3e+other+reagents

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Stain-Free, Rapid, and Quantitative Viral Plaque Assay Using Deep Learning and Holography (Case No. 2022-326)

Intro Sentence: UCLA researchers in the Department of Electrical and Computer Engineering have developed a rapid and stain-free quantitative assay using lens-free holography and deep learning to efficiently and cost-effectively determine the presence of viral plaque-forming units (PFUs) in samples. Background: A broad range of viruses have caused...

Published: 3/7/2024 | Inventor(s): Aydogan Ozcan, Yuzhu Li, Tairan Liu

Keywords(s): Antiviral Drug, Artifical Intelligence (Machine Learning, Data Mining), Assay, Bioassay, Computer Aided Learning, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Digital Holography, Electrical, Electrical Brain Stimulation, Electrical Breakdown, Electrical Engineering, Electrical Impedance, Electrical Load, Electrical Load Equation Of State, Electrical Resistance And Conductance, Electrical Resistivity And Conductivity, Holography, Immunoassay, Immunoassay Sense (Molecular Biology), Lentivirus Viral Vector, Machine Learning, Machine Learning Autonomous Car Gradient Descent, Machine Learning Pain Management, Machine Learning Particulates Global Climate Model, Network Analysis (Electrical Circuits), Perceptual Learning, Plasmid Trabecular Meshwork Aqueous Humour Viral Vector, Targets And Assays, Transcutaneous Electrical Nerve Stimulation, Transfection Viral Vector, Unsupervised Learning , Viability Assay, Viral Delivery Systems, Viral Envelope, Viral Load

Category(s): Diagnostic Markers, Diagnostic Markers > Targets And Assays, Electrical, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Software & Algorithms > Artificial Intelligence & Machine Learning

2023-102 A Dynamic Cholesteric Liquid Crystal for Organoid, Spheroid, 3D Cell Aggregate Manufacturing

Summary: UCLA and University of Connecticut researchers have engineered a novel liquid-crystal-based biomaterial with a simple fabrication process for organoid, spheroid and 3D cell aggregate manufacturing that enables rapid cell growth. Background: The current waiting list for people who need a lifesaving organ transplant is over 100,000 cases...

Published: 7/19/2023 | Inventor(s): Paul Weiss, Amir Nasajpour, Ali Tamayol, Mohamadmahdi Samandari

Keywords(s): 3D biofabrication, 3D Printing, Biocompatibility, biocompatible, Biomaterial 3D Printing, biomedical implantation, Cell and tissue culture, Cell Culture, cell-extracellular matrix (ECM), cellular aggregates, Cellular agriculture, Cholesterol, cholesteryl ester liquid crystals (CLCs), Cultured meat, Electrode 3D Printing, liquid crystal, liquid crystal nanofibers, mesogens, Organ Transplant, organogenesis, scaffolds, self-assemble, Stem Cells / Regenerative Medicine, Tissue Engineering

Category(s): Chemical, Chemical > Polymers, Materials, Materials > Functional Materials, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Medical Devices, Medical Devices > Surgical Tools, Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

2021-016 Liquid Crystal-based Scaffolds for Cell-cultured Meat Production

Summary: UCLA researchers in the Department of Mechanical and Materials Engineering have developed a nonwoven CLC (cholesteryl ester liquid crystals) electrospun scaffold to enhance myofibril formation in vitro. Background: Cholesteryl ester liquid crystals (CLCs) are promising biomaterials for the development of dynamic and responsive interfaces...

Published: 7/19/2023 | Inventor(s): Amir Nasajpour, Paul Weiss

Keywords(s):

Category(s): Chemical > Polymers, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents

2021-309-METHODS OF USING SHAPED PARTICLES IN FLOW CYTOMETERS FOR ASSAYS ON B CELLS AND T CELLS

Summary: UCLA researchers in the Department of Bioengineering have developed a platform to sort single cells based on their secreted product at high throughput using commonly accessible lab infrastructure, i.e., flow cytometers. Background: Techniques to sort single cells based on secreted products have the potential to accelerate the development...

Published: 7/19/2023 | Inventor(s): Dino Di Carlo, Joseph de Rutte, Robert Dimatteo, Maani Archang, Robert Damoiseaux, Doyeon Koo

Keywords(s): Antibody, B Cell, Bioassay, Cell Counting/Imaging, Cellular Differentiation, Cytometry, Flow Cytometry, Fluorescence, Hybridoma Technology, Secretory Component, T Cell, Targets And Assays

Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Life Science Research Tools > Cell Lines, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies

2020-849-LOW-COST, FAST AND COMPACT EXHALED BREATH CONDENSATE TECHNOLOGY

SUMMARY: UCLA researchers have developed a low-cost method for non-invasive infectious disease testing that can monitor large public spaces for signs of viral outbreaks. BACKGROUND: The ability to test for infectious diseases through non-invasive approaches has become even more prevalent today due to the COVID-19 pandemic. To monitor large populations...

Published: 7/19/2023 | Inventor(s): Pirouz Kavehpour

Keywords(s): Diagnostic Test, Infection, Infectious Diseases, Infectivity, Medical Device, Viral Load

Category(s): Life Science Research Tools > Other Reagents, Diagnostic Markers, Therapeutics > Infectious Diseases, Therapeutics > Infectious Diseases > COVID

2020-371 WNT-B-CATENIN SIGNALING PATHWAY INHIBITORS

UCLA researchers from the Department of Pediatrics have uncovered a novel inhibitor to the Wnt/β-catenin signaling pathway.BACKGROUND:Airways in the throat play a vital role in host defense to protect mammals from airborne pathogens. This protective effect is accomplished by a specialized type of epithelium, the mucocillary epithelium, that comes...

Published: 7/19/2023 | Inventor(s): Brigitte Gomperts

Keywords(s): Infectious Diseases, Life Science Research Tools, Other Reagents, Therapeutics & Vaccines

Category(s): Life Science Research Tools > Other Reagents, Therapeutics > Infectious Diseases

2011-394 Copyright: A Statistical Atlas of the Mouse Trunk Region

Summary Researchers at the University of California, Los Angeles (UCLA) have developed a comprehensive statistical atlas of the mouse trunk anatomy for use in preclinical imaging. Background Small animal imaging modalities, such as micro-CT, micro-PET, and micro-MR, are frequently used in preclinical studies. The laboratory mouse is the most widely...

Published: 7/19/2023 | Inventor(s):

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Category(s): Life Science Research Tools > Other Reagents

2011-068 A Therapeutically Relevant Culture System for Human Neural Stem-Cells and Oligodendrocytes

Summary UCLA researchers have developed a novel culture system that accelerates the propagation of neural stem cells (NSC) and their specification into oligodendrocytes (OL). The system is capable of modulating the maturational stages of OL, allowing them to reach a full myelinating state. The system also accommodates specification of human embryonic...

Published: 7/19/2023 | Inventor(s):

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Category(s): Life Science Research Tools > Other Reagents

2008-501 System to Produce Biotinylated Proteins

Summary UCLA investigators from the Department of Molecular and Medical Pharmacology have developed a system that allows the metabolic biotinylation of secreted proteins in vivo by biotin ligase, both secreted and ER-retained. This process is an improvement over traditional in vitro chemical methods, and does not alter biological functions and reduces...

Published: 7/19/2023 | Inventor(s):

Keywords(s):

Category(s): Life Science Research Tools > Other Reagents

2005-488 Reflectins, a Protein Family of Reflective Squid Tissues

Summary UCLA and University of Hawaii researchers have discovered a novel protein family with unique iridescent and reflective properties. Background Reflective tissue can be found in many marine animals. This biological advantage protects the animals from predators by altering incident light and changing visibility. In many aquatic animals this is...

Published: 7/19/2023 | Inventor(s):

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Category(s): Life Science Research Tools > Other Reagents

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