Search Results - chemical+%3e+synthesis

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Microbial de Novo Biosynthesis of Rare Cannabinoids (UCLA Case No. 2025-200)

UCLA researchers in the department of Chemical and Biomolecular Engineering have developed a microbial de novo biosynthesis platform that enables scalable production of rare cannabinoids with enhanced receptor affinity from simple sugar feedstocks. BACKGROUND: Cannabinoids are bioactive natural products that interact with the human endocannabinoid...

Published: 7/15/2026 | Inventor(s): ikechukwu okorafor, Yi Tang

Keywords(s):

Category(s): Therapeutics > Cardiovascular, Therapeutics > CNS and Neurology, Materials > Fabrication Technologies, Chemical > Synthesis, Chemical > Chemical Processing & Manufacturing

A Novel Chemical Modification of PROTACs (Proteolysis Targeting Chimeras) to Increase Selectivity in Hypoxic Environments (UCLA Case No. 2024-094)

UCLA researchers from the Department of Chemistry and Biochemistry have developed a novel chemical modification of PROTACs to increase their selectivity under hypoxic conditions. BACKGROUND: Proteolysis targeting chimeras (PROTACs) are molecules that induce targeted degradation of proteins by recruiting a ubiquitin ligase to a protein of interest...

Published: 7/15/2026 | Inventor(s): Stuart Conway

Keywords(s):

Category(s): Chemical > Synthesis, Therapeutics > Oncology

Methods for Determining Drug-Target Structures by Combining Mass Spectrometry and Electron Diffraction (UCLA Case No. 2025-229)

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel approach to study protein-ligand interactions by integrating native mass spectrometry with electron diffraction. BACKGROUND: The accurate characterization of small molecule-protein interactions is crucial for biomedical research. High-throughput structural methods,...

Published: 7/15/2026 | Inventor(s): Jose Rodriguez

Keywords(s):

Category(s): Life Science Research Tools, Life Science Research Tools > Mass Spectrometry, Chemical > Synthesis, Chemical > Chemical Sensors, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers > Targets And Assays, Electrical > Sensors, Electrical > Instrumentation, Life Science Research Tools > Research Methods, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Screening Libraries, Life Science Research Tools > Lab Equipment, Mechanical > Sensors, Mechanical > Instrumentation, Optics & Photonics > Microscopy, Optics & Photonics > Spectroscopy

Methods To Generate Constrained Fluorinated Macrocycles (UCLA Case No. 2023-139)

UCLA researchers from the Department of Chemistry and Biochemistry have developed a novel method to generate fluorinated polycycles, which may be used for downstream drug discovery and development. BACKGROUND: A significant amount of research in the field of organic chemistry centers around generating increasingly complex molecules that cyclize, forming...

Published: 7/15/2026 | Inventor(s): Patrick Harran

Keywords(s): Drug Discovery

Category(s): Chemical > Synthesis, Chemical > Catalysts

Synthesis of Heteroatom Containing Polycyclic Aromatic Hydrocarbons (Case No. 2019-232)

Summary: UCLA researchers in the Department of Chemistry & Biochemistry have developed an approach for synthesizing nitrogen-containing polycyclic aromatic hydrocarbons with high yield. Background: There is a widespread use of nitrogen-containing heterocyclic compounds in small-molecule pharmaceutical intermediates. There is also a growing need...

Published: 7/15/2026 | Inventor(s): Neil Garg, Evan Darzi, Joyann Barber

Keywords(s): Catalysts, Chemical Manufacturing & Industrial/Bulk Chemicals, Displays, Electronics & Semiconductors, Energy & Water, Optics, Photonics

Category(s): Electrical > Electronics & Semiconductors, Optics & Photonics, Materials > Semiconducting Materials, Energy & Environment > Energy Generation > Solar, Chemical > Industrial & Bulk Chemicals, Chemical > Synthesis, Electrical > Displays

Preparation of Hexahydrocannabinol (HHC) (Case No. 2023-172)

Summary: UCLA researchers in the Department of Chemistry & Biochemistry have developed a novel method to produce hexahydrocannabinols, which are derivatives of THC, the psychoactive component of cannabis. Background: As the cannabis industry evolves with changing legal and societal opinions, derivatives of the psychoactive components of marijuana,...

Published: 7/15/2026 | Inventor(s): Neil Garg, Daniel Nasrallah

Keywords(s): cannabinoid, cannabis, catalytic hydrogenation, delta 8, delta 9, diastereomer, enantioenriched, enantiospecific, hexahydrocannabinol, hexahydrocannabinols (HHC), hydrogen atom transfer, hydrogenation, marijuana, Nutraceuticals, Recreational cannabis products, tetrahydrocannabinol, THC

Category(s): Chemical, Chemical > Synthesis, Chemical > Emulsions, Therapeutics, Therapeutics > Oncology

Electrocatalysts With Tailored Local Chemical Environment for High-Performance Alkaline Water Electrolysis and Renewable Fuel Generation (Case No. 2023-212)

Summary: UCLA researchers have developed a novel catalytic system that improves reaction kinetics, durability, and resistance to impurities, making it a promising candidate for water electrolyzers and renewable chemical fuel production. Background: Hydrogen, boasting a remarkable energy density of 140 MJ/kg (nearly triple that of typical solid fuels...

Published: 7/15/2026 | Inventor(s): Xiangfeng Duan, Yu Huang, Chengzhang Wan

Keywords(s):

Category(s): Chemical, Chemical > Catalysts, Chemical > Synthesis, Materials, Materials > Nanotechnology, Materials > Functional Materials, Materials > Water Treatment, Energy & Environment, Energy & Environment > Energy Storage, Energy & Environment > Energy Storage > Fuel Cells, Energy & Environment > Energy Efficiency

Ion-Solvent-Polymer Interactions for Preparing Polymer Networks and Composites of Tunable Structures and Properties (UCLA Case No. 2023-147)

Summary: Researchers in UCLA's Department of Materials Science and Engineering have developed a solution-based synthesis platform capable of generating micro and nanostructured gels, polymers, and composites with simultaneously improved safety, mechanical and ionic conductivity/transport properties. Background: Pore structure engineering holds...

Published: 7/15/2026 | Inventor(s): Ximin He

Keywords(s):

Category(s): Chemical, Chemical > Polymers, Chemical > Synthesis, Energy & Environment, Energy & Environment > Energy Storage, Materials, Materials > Fabrication Technologies, Materials > Functional Materials, Materials > Composite Materials

Ultrafine Platinum Catalysts for Hydrogen Fuel Cells (Case No. 2023-026)

Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel method to synthesize platinum-based catalysts with ultralow base transition metal-oxide content. Background: Ultrafine platinum (Pt)-based catalysts present a promising avenue for achieving exceptional fuel cell activity while minimizing base transition...

Published: 7/15/2026 | Inventor(s): Yu Huang

Keywords(s): Catalysts, Fuel Cell, Metals, Nanoparticle, Nanoparticles, Nanotechnology, Platinum, transition metal catalysts

Category(s): Materials, Energy & Environment, Energy & Environment > Energy Storage, Energy & Environment > Energy Storage > Fuel Cells, Chemical, Chemical > Catalysts, Chemical > Synthesis, Materials > Nanotechnology

2022-130 PM-BASED CATALYST WITH TRANSITION ULTRAFINE METAL-OXIDE CORES

Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a method to synthesize uniform Pt-based catalyst nanoparticles with ultralow base transition metal content for fuel cell applications. Background: Ultrafine platinum (Pt)-based catalysts with ultralow base transition metal content can provide high fuel...

Published: 7/15/2026 | Inventor(s): Yu Huang, Xiangfeng Duan, Bosi Peng

Keywords(s): Catalysts, Energy Generation, Transmission, or Storage, Fuel Cell, Fuel Cell Membrane Electrode Assembly, Nanomaterials, Nanoparticles, Platinum

Category(s): Chemical > Catalysts, Materials > Nanotechnology, Materials > Functional Materials, Chemical > Synthesis, Energy & Environment > Energy Storage, Energy & Environment > Energy Storage > Fuel Cells

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