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Search Results - small+cell+cancer
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Bioelectric Neuromodulation Methods for Hematopoiesis Regulation During Chemotherapy (Case No. 2020-382)
Summary: UCLA researchers in the Department of Bioengineering have developed an electrical neuromodulation method to accelerate recovery from deleterious chemotherapy side effects to improve patient outcome. Background: Chemotherapy works by targeting and killing fast-growing cancer cells using anti-cancer drugs. However, because these drugs lack...
Published: 8/21/2025
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Inventor(s):
Wentai Liu
Keywords(s):
algorithmic cancer detection
,
Bladder Cancer
,
blood cancers
,
Brain cancer
,
Breast Cancer
,
Cancer
,
cancer antigen
,
cancer detection
,
Cancer Immunotherapy
,
cancer inhibition
,
cancer metabolism
,
Cancer stem cells
,
cancer target
,
castration resistant prostate cancer
,
Chemotherapy
,
head and neck cancer
,
lympathic cancers
,
lymphatic cancer
,
Mesenchymal Stem Cell Derived Cancer Cells
,
Neuromodulation
,
non-small cell lung cancer
,
Orthotopic cancer models
,
Pancreatic cancer
,
prostate cancer
,
small cell cancer
,
small cell lung cancer
,
small cell prostate cancer
Category(s):
Medical Devices
,
Medical Devices > Neural Stimulation
,
Chemical
,
Electrical
,
Therapeutics
,
Therapeutics > Oncology
Temporal Transcriptomic Characterization of Small Cell Neuroendocrine Prostate Cancer (UCLA Case No. 2023-268)
The laboratory of Dr. Thomas Graeber at UCLA developed a novel in vivo model that can characterize mechanisms of the trans-differentiation of prostate cancer into small cell neuroendocrine cancer. BACKGROUND: Prostate cancer is one of the most common cancers among men worldwide, with an estimated 288,300 new cases in the U.S. last year. Among many...
Published: 7/31/2025
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Inventor(s):
Thomas Graeber
Keywords(s):
neuroendocrine
,
Oncology
,
prostate cancer
,
small cell cancer
,
transdifferentiation
Category(s):
Therapeutics > Oncology > Oncology (Small Molecules)
,
Platforms > Diagnostic Platform Technologies
Human T-Cell Receptors Targeting Tumor-Enhanced Splicing Epitopes on HLA-A for Small Cell Carcinoma (UCLA Case Nos. 2023-117, 2020-817)
UCLA Researchers in the Department of Microbiology, Immunology, & Molecular Genetics have utilized their previously developed computational method (IRIS), to process and capture small cell carcinoma-specific RNA splicing events in
small cell cancer
. These events and associated epitopes were then used as the basis for generating new T cell receptors...
Published: 7/31/2025
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Inventor(s):
Owen Witte
Keywords(s):
alternative splicing
,
Cancer
,
prostate cancer
,
RNA splicing
,
small cell
,
small cell cancer
,
small cell lung cancer
,
small cell prostate cancer
,
Targets And Assays
Category(s):
Life Science Research Tools