Search Results - stem+cells+%2f+regenerative+medicine

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A Novel “Host-Guest”-Based Supramolecular Hydrogel for Dental Pulp Regeneration (Case No. 2023-154)

Summary: Researchers in the Department of Dentistry at UCLA have developed an innovative hydrogel for a vast array of biomedical and tissue engineering applications. Background: Hydrogels have emerged as powerful tools in biomedical engineering due to their ability to provide a supportive environment for cell growth, tissue repair, and drug delivery....

Published: 10/14/2024 | Inventor(s): Alireza Moshaverinia, Weihao Yuan

Keywords(s): anti-dehydration, Drug Delivery, dynamic identification, hydrogel, Stem Cells / Regenerative Medicine, Targeted Therapy, tissue regeneration

Category(s): Chemical, Materials > Functional Materials, Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Platforms > Drug Delivery > Nanoparticles, Platforms > Drug Delivery > Viral Delivery Systems, Therapeutics > Cell Therapy, Therapeutics > Medication, Therapeutics > Stem Cells And Regenerative Medicine

Multiwell Plate-Based Flow Culture for Improving the Quality of 3D Tissues (Case No. 2022-067)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a simple, innovative method for growing 3D cell cultures with improved organoid differentiation and reduced hypoxia-induced cell death. TITLE: Multiwell Plate-Based Flow Culture for Improving the Quality of 3D Tissues Background: 3D tissue culture,...

Published: 10/23/2024 | Inventor(s): Neil Lin, Marie Payne

Keywords(s): 3D Printing, Biofilm, Biomaterial 3D Printing, Biomedical Engineering, Cancer, cancer detection, Cancer Immunotherapy, Cell and tissue culture, Cell Culture, Cellular agriculture, Cultured meat, iPS/stem cells, Laminar flow, Microwell plates, organogenesis, Organoids, Personalized Pharmacotherapy, Pharmaceutical testing, Stem Cells / Regenerative Medicine, Tissue (Biology), tissue detection, Tissue Engineering, Tissue sedimentation

Category(s): Life Science Research Tools > Lab Equipment, Life Science Research Tools, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Therapeutics, Therapeutics > Oncology

2023-102 A Dynamic Cholesteric Liquid Crystal for Organoid, Spheroid, 3D Cell Aggregate Manufacturing

Summary: UCLA and University of Connecticut researchers have engineered a novel liquid-crystal-based biomaterial with a simple fabrication process for organoid, spheroid and 3D cell aggregate manufacturing that enables rapid cell growth. Background: The current waiting list for people who need a lifesaving organ transplant is over 100,000 cases...

Published: 7/19/2023 | Inventor(s): Paul Weiss, Amir Nasajpour, Ali Tamayol, Mohamadmahdi Samandari

Keywords(s): 3D biofabrication, 3D Printing, Biocompatibility, biocompatible, Biomaterial 3D Printing, biomedical implantation, Cell and tissue culture, Cell Culture, cell-extracellular matrix (ECM), cellular aggregates, Cellular agriculture, Cholesterol, cholesteryl ester liquid crystals (CLCs), Cultured meat, Electrode 3D Printing, liquid crystal, liquid crystal nanofibers, mesogens, Organ Transplant, organogenesis, scaffolds, self-assemble, Stem Cells / Regenerative Medicine, Tissue Engineering

Category(s): Chemical, Chemical > Polymers, Materials, Materials > Functional Materials, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Medical Devices, Medical Devices > Surgical Tools, Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

2020-443 A PATCH OF DETACHABLE HYBRID MICRONEEDLE DEPOT (D-HMND) FOR LOCALIZED DELIVERY OF MESENCHYMAL STEM CELLS IN REGENERATION THERAPY

UCLA researchers in the Department of Bioengineering have developed a novel detachable hybrid microneedle depot (d-HMND) for the targeted delivery of mesenchymal stem cells. BACKGROUND: Stem cell biology has been widely applied to the treatment of tissue damage, due to the ability of stem cells to form, repair, and maintain tissues and organs after...

Published: 7/19/2023 | Inventor(s): Ali Khademhosseini

Keywords(s): iPS/stem cells, Life Science Research Tools, Stem Cells / Regenerative Medicine, Therapeutics & Vaccines

Category(s): Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

2017-529 Titanium Implants with Novel Roughness

SUMMARY: UCLA researchers in the School of Dentistry at the Weintraub Center for Reconstructive Biology have developed a novel titanium implant with hierarchical multi-scale roughness to promote bone growth. BACKGROUND: Titanium implants are used as a scaffold to regenerate bone. Degeneration and injury of bone, joints, and jaw are on a rapid increase...

Published: 7/24/2024 | Inventor(s): Takahiro Ogawa

Keywords(s): Dental, Medical Devices and Materials, Orthopaedics, Stem Cells / Regenerative Medicine

Category(s): Medical Devices, Therapeutics > Dental

2018-465 ANTIBODY-FREE PROTOCOL FOR GENERATION OF HIGHLY EXPANDABLE, NON-FIBROADIPOGENIC MESODERMAL PRECURSORS FROMHUMAN PLURIPOTENT STEM CELLS FOR TREATMENT

Antibody-Free Protocol For Generation Of Highly Expandable, Non-Fibroadipogenic Mesodermal Precursors from Human Pluripotent Stem Cells For TreatmentTech ID: 30170 / UC Case 2018-465-0SUMMARYUCLA researchers in the Department of Orthopaedic Surgery have developed a novel method to generate mesodermal precursors from human pluripotent stem cells to treat...

Published: 7/19/2023 | Inventor(s): Ayelet Dar, Bruno Peault, Frank Petrigliano

Keywords(s): Musculoskeletal Disease, Stem Cells / Regenerative Medicine, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Musculoskeletal Disease

2004-084 Adipose Derived Stem Cells for Reconstruction of the Urinary Tract

Stem Cell Urinary Tract Reconstruction TherapySUMMARYResearchers from the UCLA Department of Urology have successfully harvested stem cells from adipose tissue and differentiate them into functioning smooth muscle cells. These adipose derived stem cells can then be used for reconstruction or tissue engineering of smooth muscle containing organs, especially...

Published: 7/19/2023 | Inventor(s): Benjamin Wu, Larissa Rodriguez

Keywords(s): iPS/stem cells, Renal, Stem Cells / Regenerative Medicine, Urology

Category(s): Therapeutics > Urology, Therapeutics > Renal, Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

2017-527 Titanium Plates for Bone Regeneration

Titanium Plates For Bone RegenerationSUMMARYUCLA researchers in the School of Dentistry at the Weintraub Center for Reconstructive Biology have developed a new titanium plate to promote bone regeneration in dental reconstruction procedures.BACKGROUNDTitanium plates are used as a scaffold to regenerate bone. In the case of dental implants, titanium plates...

Published: 11/20/2024 | Inventor(s): Takahiro Ogawa

Keywords(s): Dental, Medical Devices and Materials, Stem Cells / Regenerative Medicine

Category(s): Medical Devices, Therapeutics > Dental