Search Results - therapeutics+%3e+immunology+and+immunotherapy

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Methods and Agents for Modulating the Immune Response (UCLA Case No. 2020-864)

Full description coming soon. Please contact UCLA Technology Development Group (TDG) for more information.

Published: 10/3/2025 | Inventor(s): Stephen Smale

Keywords(s):

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Vaccines

Antiviral Compounds Inhibiting Zika Virus (ZIKV), and Methods and Zika Treatment Thereof (UCLA Case No. 2025-241)

UCLA researchers from the Molecular and Medical Pharmacology Department and CNSI have identified antiviral compounds that effectively inhibit Zika virus infection and cytopathic effects, potentially leading to improved therapeutics and treatment outcomes. BACKGROUND: Zika virus (ZIKV), a flavivirus now endemic to several regions globally, can cause...

Published: 10/3/2025 | Inventor(s): Vaithilingaraja Arumugaswami, Robert Damoiseaux

Keywords(s):

Category(s): Life Science Research Tools > Screening Libraries, Diagnostic Markers > Immunology, Diagnostic Markers > Targets And Assays, Therapeutics > Infectious Diseases, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Platforms > Diagnostic Platform Technologies

IL-2 Independent Ultrahigh Human T Cell Activations Through Biomimetics of Immune Synapses by Graphene Oxides (UCLA Case No. 2021-068)

UCLA researchers in the Department of Materials Science and Engineering have constructed a novel graphene oxide-based platform for robust T cell activation through artificial immune synapse formation. BACKGROUND: T cells are a critical arm of the immune system with tremendous therapeutic value for immune disorders and cancer. However, modulation of...

Published: 10/2/2025 | Inventor(s): Yu Huang, Lili Yang

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

Methods and Compositions for Promoting Anti-Tumor Immunity of T Cells (UCLA Case No. 2026-037)

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Published: 9/19/2025 | Inventor(s): Alexandra Nicoleta Boix De Jesus, Joseph Crompton, Hy Dao

Keywords(s):

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology

Catch Bond-Enhanced Human T Cell Receptors Targeting Prostatic Acid Phosphatase on HLA-A*02:01 (UCLA Case No. 2025-138)

UCLA researchers from the Department of Microbiology, Immunology, and Molecular Genetics and Stanford researchers from the Department of Molecular and Cellular Physiology have developed novel enhanced T cell receptors engineered to specifically recognize prostatic acid phosphatase, offering a powerful and precise immunotherapeutic strategy for prostate...

Published: 9/19/2025 | Inventor(s): Owen Witte, Zhiyuan Mao, John Lee, Kenan Christoph Garcia

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

Self-Amplifying RNA Form of a Constitutively-Active Sting Protein for Enhancing T-Cell Response to Antigen-Presenting Cells (UCLA Case No. 2020-771)

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Published: 9/24/2025 | Inventor(s): William Gelbart

Keywords(s): Adenoviridae

Category(s): Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy

In Vivo CAR-T-Cell Transformation Using mRNA-Containing in Vitro Reconstituted Virus-Like Particles (UCLA Case No. 2024-057)

Contact UCLA Technology Development Group to learn more. More info available soon.

Published: 9/18/2025 | Inventor(s): William Gelbart

Keywords(s):

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy

Double-Stranded RNA Expression Signatures to Predict Response to Cancer Therapy (UCLA Case No. 2022-218)

UCLA researchers from the Department of Integrative Biology and Physiology have developed a novel method to profile RNA editing in single cells from lung cancer biopsies as a method to predict patient survival. BACKGROUND: RNA editing occurs naturally in the human transcriptome and has been shown to influence cancer cell behavior and the anti-tumor...

Published: 9/17/2025 | Inventor(s): Xinshu Xiao, Ting Fu

Keywords(s):

Category(s): Diagnostic Markers > Cancer, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

Older Individuals Lack Adequate Function of NK Cells and Can Not Expand SNK Cells When Compared to Younger Individuals; Reversal by Infusion of SNKs (UCLA Case No. 2025-018)

Please contact UCLA Technology Development Group for more information. KEYWORDS: immunotherapy, natural killer cells, cell therapy, immunity, geriatric immune rejuvenation, cancer adjunct therapy, immunosenescence

Published: 9/23/2025 | Inventor(s): Anahid Jewett

Keywords(s):

Category(s): Therapeutics > Cell Therapy, Therapeutics > Immunology And Immunotherapy

Engineered Mucosal-Associated Invariant T (MAIT) Cells and Methods of Making and Using Thereof (UCLA Case No. 2024-055)

UCLA researchers in the Department of Microbiology Immunology and Molecular Genetics have developed a novel platform and methodology for the production of mucosal-associated invariant T (MAIT) cells for therapeutic use in infectious diseases, autoimmune disorders, and cancer. BACKGROUND: Mucosal-associated invariant T (MAIT) cells are a subset of...

Published: 7/31/2025 | Inventor(s): Lili Yang

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Infectious Diseases, Therapeutics > Immunology And Immunotherapy, Therapeutics > Autoimmune

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