Search Results - platforms+%3e+diagnostic+platform+technologies

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Method and Apparatus for Acceleration of Dense MR Data Acquisition (Case No. 2025-226)

Summary: UCLA researchers from the Department of Radiological Sciences have developed a novel acquisition and reconstruction strategy that accelerates Displacement Encoding with Stimulated Echoes (DENSE) MRI, enabling faster and clinically feasible cardiac strain measurement. Background: Myocardial strain is an important biomarker for assessing how...

Published: 10/8/2025 | Inventor(s): Xiaodong Zhong, Shu-Fu Shih

Keywords(s):

Category(s): Electrical > Imaging, Electrical > Signal Processing, Medical Devices > Cardiac, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Platforms > Diagnostic Platform Technologies, Software & Algorithms > Data Analytics, Software & Algorithms, Software & Algorithms > Image Processing

Use of Blood, Bronchoalveolar Lavage Fluid (BALF) or Urine Cytokines Combined With Donor-Derived Cell-Free DNA (dd-cfDNA) as a Biomarker of Allograft (UCLA Case No. 2025-316)

UCLA researchers in the Department of Pulmonology have identified a novel non-invasive combinatorial biomarker for prediction, early detection, and monitoring of acute and chronic allograft injury. BACKGROUND: Post-surgery treatment and rejection surveillance for solid organ transplantation remains challenging, primarily due to a limited ability to...

Published: 10/3/2025 | Inventor(s): Yusaku Shino

Keywords(s):

Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Platforms > Diagnostic Platform Technologies

Antiviral Compounds Inhibiting Zika Virus (ZIKV), and Methods and Zika Treatment Thereof (UCLA Case No. 2025-241)

UCLA researchers from the Molecular and Medical Pharmacology Department and CNSI have identified antiviral compounds that effectively inhibit Zika virus infection and cytopathic effects, potentially leading to improved therapeutics and treatment outcomes. BACKGROUND: Zika virus (ZIKV), a flavivirus now endemic to several regions globally, can cause...

Published: 10/3/2025 | Inventor(s): Vaithilingaraja Arumugaswami, Robert Damoiseaux

Keywords(s):

Category(s): Life Science Research Tools > Screening Libraries, Diagnostic Markers > Immunology, Diagnostic Markers > Targets And Assays, Therapeutics > Infectious Diseases, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Platforms > Diagnostic Platform Technologies

A Nanoengineered Immunosensor to Detect Multiple Circulating Biomarkers for Rapid Prediction of Acute Thrombosis (UCLA Case No. 2025-015)

Contact UCLA Technology Development Group to learn more.

Published: 9/24/2025 | Inventor(s): Tzung Hsiai

Keywords(s):

Category(s): Diagnostic Markers, Materials > Nanotechnology, Platforms > Diagnostic Platform Technologies, Therapeutics > Cardiovascular

A Cell-Free DNA Biomarker for Diagnosis and Prognosis of Diseases with Degenerative Processes (UCLA Case No. 2023-250)

UCLA researchers led by Professor Noah Zaitlen in the Departments of Computational Medicine and Neurology have developed a cutting-edge platform for leveraging cfDNA molecular signatures as powerful biomarkers, advancing early diagnosis and prognosis in degenerative diseases through a minimally invasive, highly sensitive liquid biopsy method. INNOVATION:...

Published: 9/12/2025 | Inventor(s): Noah Zaitlen

Keywords(s):

Category(s): Platforms > Diagnostic Platform Technologies, Diagnostic Markers, Therapeutics > CNS and Neurology

DNA Methylation-Based Algorithm to Diagnose Irritable Bowel Syndrome and Other GI Conditions (UCLA Case No. 2022-229)

UCLA researchers in the Department of Gastroenterology have developed a DNA methylation-based algorithm to diagnose irritable bowel syndrome and other GI conditions. Blood-based genome-wide DNA methylation profiles have been utilized to develop a reliable test to diagnose irritable bowel syndrome (IBS) versus inflammatory bowel disease (IBD), celiac...

Published: 9/11/2025 | Inventor(s): Lin Chang, Swapna Joshi

Keywords(s):

Category(s): Therapeutics > Gastroenterology, Platforms > Diagnostic Platform Technologies

Physical Separation of Ultrashort Single-Stranded Cell-Free DNA in Biofluids Using Differential Filtration and Next-Generation Sequencing Pipeline to Detect Methylation Status of Ultrashort Single-Stranded Cell-Free DNA (UCLA 2023-077, 2023-082)

UCLA researchers in the Department of Dentistry have established novel extraction and bioinformatics pipeline of ultrashort single-stranded cell-free DNA for the use in liquid biopsy diagnostics. BACKGROUND: Liquid biopsy is a critical diagnostic tool for various human diseases. The rapid market growth of liquid biopsy is primarily driven by novel...

Published: 9/11/2025 | Inventor(s): David Wong, Jordan Cheng

Keywords(s): Cancer, cell-free DNA, circulating DNA, Diagnostic Markers & Platforms, DNA methylation, liquid biopsy, next generation sequencing (NGS)

Category(s): Software & Algorithms > Bioinformatics, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies

Analysis of Ultrashort Single-Stranded Cell-Free DNA in Patient Saliva for Disease Detection (UCLA Cases 2022-292, 2022-043)

UCLA researchers have developed a novel next-generation sequencing (NGS) pipeline designed specifically to detect ultrashort single-stranded cell-free DNA (uscfDNA), providing significant advancements in sensitivity, clinical utility, and genomic research applications. Background: Cell-free DNA (cfDNA) fragments circulate in body fluids and have become...

Published: 9/11/2025 | Inventor(s): David Wong, Jordan Cheng

Keywords(s):

Category(s): Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies

A Diagnostic Epigenetic Score for Determining the Effect of Biomarkers for Asthma Drug Response (UCLA Case No. 2024-106)

UCLA researchers in the Department of Computational Medicine have developed a novel machine learning algorithm to generate an accurate molecular score for determining asthma drug response. BACKGROUND: Asthma is a globally prevalent, high-burden disease marked by substantial clinical heterogeneity and variable treatment response. This heterogeneity...

Published: 7/17/2025 | Inventor(s): Elior Rahmani

Keywords(s):

Category(s): Platforms > Diagnostic Platform Technologies, Diagnostic Markers > Targets And Assays, Software & Algorithms > AI Algorithms, Software & Algorithms > Digital Health, Therapeutics > Inflammation And Inflammatory Diseases

Non-invasive Pain Measurement of Infants and Toddlers Using Acoustic Features of Cries (Copyright; Case No. 2018-327)

Summary: Researchers in the UCLA Semel Institute for Neuroscience and Human Behavior have developed a novel, non-invasive pain measurement tool for neonates. Background: Pain management in neonatal care remains a critical unmet need. Approximately 90% of premature infants undergo painful procedures, yet pain is only reported in 45% of cases. Current...

Published: 4/21/2025 | Inventor(s): Ariana Anderson

Keywords(s): acoustics, artificial intelligence/machine learning models, Digital Signal Processing, Machine Learning Pain Management, Monitoring (Medicine), non-invasive monitoring, Pain Treatment, pediatrics

Category(s): Diagnostic Markers > Pediatrics, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > AI Algorithms, Software & Algorithms > Data Analytics, Software & Algorithms > Digital Health, Therapeutics > Critical Care, Therapeutics > Psychiatry And Mental Health

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