Search Results - platforms+%3e+diagnostic+platform+technologies

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Compositions and Methods to Modulate MAVS-Mediated Immunity (UCLA Case No. 2026-096)

UCLA researchers in the Department of Microbiology, Immunology, and Molecular Genetics have developed methods to target TOM70, a mitochondrial outer membrane protein, to selectively modulate innate immune signaling and control pathological or protective immune responses across a range of clinical conditions. BACKGROUND: Innate immune detection of viral...

Published: 2/18/2026 | Inventor(s): Lena Pernas

Keywords(s):

Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology, Therapeutics > Infectious Diseases, Therapeutics > Immunology And Immunotherapy, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Autoimmune, Therapeutics > Vaccines

Highly Miniaturized Closed-Loop Biosensing and Drug Delivery (Case No. 2025-276)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an implantable closed-loop system that integrates electrochemical biosensing, wireless signal transmission, and programmable drug release. Background: Conventional disease management systems rely on single-point measurements and discrete interval drug...

Published: 2/5/2026 | Inventor(s): Aydin Babakhani, Iman Habibagahi, Hamid Jafarisharemi, Roshan Mathews

Keywords(s): biomedical implantation, biomedical sensors, Drug Delivery, Drug monitoring, Implant (Medicine), implantable sensors, Medical Device, minimally invasive drug delivery systems, on-demand drug delivery, personalized dose assessment, Smart medical device, Therapeutics, wearable, wearable electronics, wearable medical device, wearable medical devices, wearable sensors, wearable sensors for health, Wireless, wireless communication

Category(s): Life Science Research Tools, Electrical, Medical Devices, Platforms > Diagnostic Platform Technologies, Platforms > Drug Delivery, Platforms

An Acoustic Device for Large Area Single Cell Trapping and Selective Release (Case No. 2025-047)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed an acoustic microfluidic platform that offers a cost-effective and practical approach for handling individual cells at the microscale. Background: Single-cell manipulation is essential for understanding cellular behavior, disease progression, and therapeutic...

Published: 1/13/2026 | Inventor(s): Pei-Yu Chiou, Xiang Zhang

Keywords(s): acoustic microfluidics, acoustic potential wells, acoustics, cell proliferation, cell viability, Diagnostic Platform Technologies (E.G. Microfluidics), diagnostic platforms, Digital Microfluidics, disposable microfluidic platforms, high throughput, high throughput assays, high throughput testing, High-Content Screening, high-throughput cell handling, low-cost fabrication, MEMS, MEMS metasurface, micro-electromechanical systems (MEMS), Microfluidics, Microfluidics And Mem's, Microfluidics Dielectrophoresis, Microfluidics Multi-Band Device, Microfluidics Nanosphere, near-infrared laser, photolithography-free fabrication, research instrumentation, scalable platform, single cell analysis, single cell analysis and testing, Single cell data, single-cell handling, single-cell manipulation, single-cell resolution, single-cell trapping

Category(s): Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Mechanical, Mechanical > Instrumentation, Platforms, Platforms > Diagnostic Platform Technologies

Oral-Gut-Brain Axis Virome/Microbiome for Periodontitis, Irritable Bowel Disease and Alzheimer’s Disease Diagnostics (UCLA Case No. 2024-222)

UCLA researchers in the School of Dentistry and section of Biosystems and Function have developed a novel diagnostic protocol to accurately categorize both the virome and microbiome of the oral-gut-brain axis for periodontitis, irritable bowel disease, and Alzheimer’s disease pathologies. BACKGROUND: Humans are host to a large and diverse set...

Published: 1/7/2026 | Inventor(s): Yvonne Kapila

Keywords(s):

Category(s): Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies

Method and Apparatus for Acceleration of Dense MR Data Acquisition (Case No. 2025-226)

Summary: UCLA researchers from the Department of Radiological Sciences have developed a novel acquisition and reconstruction strategy that accelerates Displacement Encoding with Stimulated Echoes (DENSE) MRI, enabling faster and clinically feasible cardiac strain measurement. Background: Myocardial strain is an important biomarker for assessing how...

Published: 11/19/2025 | Inventor(s): Xiaodong Zhong, Shu-Fu Shih

Keywords(s):

Category(s): Electrical > Imaging, Electrical > Signal Processing, Medical Devices > Cardiac, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Platforms > Diagnostic Platform Technologies, Software & Algorithms > Data Analytics, Software & Algorithms, Software & Algorithms > Image Processing

Use of Blood, Bronchoalveolar Lavage Fluid (BALF) or Urine Cytokines Combined With Donor-Derived Cell-Free DNA (dd-cfDNA) as a Biomarker of Allograft (UCLA Case No. 2025-316)

UCLA researchers in the Department of Pulmonology have identified a novel non-invasive combinatorial biomarker for prediction, early detection, and monitoring of acute and chronic allograft injury. BACKGROUND: Post-surgery treatment and rejection surveillance for solid organ transplantation remains challenging, primarily due to a limited ability to...

Published: 10/3/2025 | Inventor(s): Yusaku Shino

Keywords(s):

Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Platforms > Diagnostic Platform Technologies

Antiviral Compounds Inhibiting Zika Virus (ZIKV), and Methods and Zika Treatment Thereof (UCLA Case No. 2025-241)

UCLA researchers from the Molecular and Medical Pharmacology Department and CNSI have identified antiviral compounds that effectively inhibit Zika virus infection and cytopathic effects, potentially leading to improved therapeutics and treatment outcomes. BACKGROUND: Zika virus (ZIKV), a flavivirus now endemic to several regions globally, can cause...

Published: 10/3/2025 | Inventor(s): Vaithilingaraja Arumugaswami, Robert Damoiseaux

Keywords(s):

Category(s): Life Science Research Tools > Screening Libraries, Diagnostic Markers > Immunology, Diagnostic Markers > Targets And Assays, Therapeutics > Infectious Diseases, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Platforms > Diagnostic Platform Technologies

A Nanoengineered Immunosensor to Detect Multiple Circulating Biomarkers for Rapid Prediction of Acute Thrombosis (UCLA Case No. 2025-015)

UCLA researchers in the Department of Cardiology have developed a nanoengineered immune sensor that uses machine learning to detect multiple circulating biomarkers for rapid, accurate prediction of acute thrombosis. BACKGROUND: Acute thrombosis represents a significant contributor to both acute and chronic illnesses. Moreover, the correlation between...

Published: 11/25/2025 | Inventor(s): Tzung Hsiai

Keywords(s):

Category(s): Materials > Nanotechnology, Platforms > Diagnostic Platform Technologies, Therapeutics > Cardiovascular, Diagnostic Markers > Targets And Assays, Medical Devices > Monitoring And Recording Systems, Software & Algorithms > Artificial Intelligence & Machine Learning

A Cell-Free DNA Biomarker for Diagnosis and Prognosis of Diseases with Degenerative Processes (UCLA Case No. 2023-250)

UCLA researchers led by Professor Noah Zaitlen in the Departments of Computational Medicine and Neurology have developed a cutting-edge platform for leveraging cfDNA molecular signatures as powerful biomarkers, advancing early diagnosis and prognosis in degenerative diseases through a minimally invasive, highly sensitive liquid biopsy method. INNOVATION:...

Published: 9/12/2025 | Inventor(s): Noah Zaitlen

Keywords(s):

Category(s): Platforms > Diagnostic Platform Technologies, Diagnostic Markers, Therapeutics > CNS and Neurology

DNA Methylation-Based Algorithm to Diagnose Irritable Bowel Syndrome and Other GI Conditions (UCLA Case No. 2022-229)

UCLA researchers in the Department of Gastroenterology have developed a DNA methylation-based algorithm to diagnose irritable bowel syndrome and other GI conditions. Blood-based genome-wide DNA methylation profiles have been utilized to develop a reliable test to diagnose irritable bowel syndrome (IBS) versus inflammatory bowel disease (IBD), celiac...

Published: 9/11/2025 | Inventor(s): Lin Chang, Swapna Joshi

Keywords(s):

Category(s): Therapeutics > Gastroenterology, Platforms > Diagnostic Platform Technologies

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