Search Results - chen+chen

68 Results Sort By:
A Ventilated Artificial Human Lung Exposure System to Analyze and Test Human Exposures to Inhaled Substances (Case No. 2023-306)
Summary: UCLA researchers in the Department of Medicine and Environmental Health Sciences have developed a ventilated human lung system for laboratory testing of inhaled substances. Background: Measuring the toxicology of inhaled air, aerosols and other substances is challenging due to the complexity of human studies and limitations in existing...
Published: 3/27/2025   |   Inventor(s): Michael Roth, Airi Harui, Yifang Zhu, Haoxuan Chen
Keywords(s): aerosol, Angiogenesis Acute Lung Injury, bioaerosol, cardiopulmonary illness, Cellular Respiration, consumer goods and products, Lung, Lung Pulmonology, non-small cell lung cancer, Preclinical model development, Preclinical surgical innovation, pulmonary arterial pressure (PAP), pulmonary failure, Pulmonary fibrosis, Respiratory & Pulmonary, respiratory failure, right atrial to pulmonary canula, Simulation & Modeling, simulation model, small cell lung cancer
Category(s): Platforms, Platforms > Drug Delivery, Life Science Research Tools, Life Science Research Tools > Research Methods, Therapeutics, Therapeutics > Respiratory And Pulmonary, Mechanical, Mechanical > Sensors
Single-Chain Bispecific Chimeric Antigen Receptor Targeting BCMA and CS1 for the Treatment of Multiple Myeloma (UCLA Case No. 2018-680)
UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a single-chain bispecific chimeric antigen receptor targeting BCMA and CS1 for treating multiple myeloma. BACKGROUND: Multiple myeloma (MM) is a cancer of the plasma cells that accounts for over 30,000 new diagnoses each year, according to the American Cancer...
Published: 2/19/2025   |   Inventor(s): Yvonne Chen, Eugenia Zah
Keywords(s): Hematology, Immunotherapy, Life Science Research Tools, Therapeutics & Vaccines
Category(s): Life Science Research Tools, Therapeutics > Immunology And Immunotherapy, Therapeutics > Hematology
Methods to Improve Chimeric Antigen Receptor (CAR)-T Cell Efficacy Through Rational Sequence and Structural Modifications (UCLA Case No. 2020-497)
UCLA researchers in the Department of Microbiology, Immunology & Molecular Genetics have developed novel engineering methodologies for CAR molecules that overcome the tonic signaling process that leads to T cell exhaustion and poor therapy efficacy. Background: Immunotherapy has become a highly effective method to combat cancer that enhances a...
Published: 2/14/2025   |   Inventor(s): Yvonne Chen
Keywords(s): Cancer Immunotherapy
Category(s): Therapeutics > Oncology > Oncology Immunotherapy
Liquid Metal Printing Technique via Optical Maskless Lithography (Case No. 2024-031)
Summary: Researchers in the UCLA Department of Materials Science and Engineering have developed a facile, rapid method to print soft, wearable electronics. Background: Soft electrical circuits have garnered significant interest in a broad range of emerging technologies, including wearable electronics, brain-machine interfaces, and soft robotics....
Published: 3/6/2025   |   Inventor(s): Ximin He, Dong Wu
Keywords(s): Coating, Coatings, Adhesives, & Inks, Electronics & Semiconductors, Fabrication Technologies, gallium-based liquid metals, General Device Coatings, Liquid metal particles, liquid metals, Metals, Microelectronics Semiconductor Device Fabrication, Polymer, Polymers, scalable fabrication, Semiconductor Device Fabrication, soft electrical circuits, soft electronics, wearable electronics, wearable sensors
Category(s): Chemical, Chemical > Polymers, Chemical > Coatings, Adhesives & Inks, Electrical, Electrical > Electronics & Semiconductors, Electrical > Sensors, Electrical > Instrumentation, Electrical > Flexible Electronics, Materials, Materials > Fabrication Technologies, Materials > Composite Materials, Materials > Metals
Discovering Permanent Fluidic Magnets for Liquid Bioelectronics (Case No. 2024-083)
Summary: UCLA researchers from the Department of Bioengineering have developed a permanent fluidic magnet that maintains stable colloids for application in a variety of fields, including physiological monitoring and bioelectronics. Background: Colloid suspensions are comprised of dispersed small solid particles in fluids. The stability of a colloid...
Published: 3/20/2025   |   Inventor(s): Jun Chen
Keywords(s):  
Category(s): Materials, Materials > Functional Materials, Materials > Membranes, Electrical, Electrical > Mems, Materials > Nanotechnology, Platforms, Platforms > Drug Delivery
Engineered T Cells Capable of Simultaneous Tumor Targeting and Alteration of Tumor Microenvironment Through Vasculature Normalization (UCLA Case No. 2023-264)
UCLA researchers in the Department of Microbiology, Immunology and Molecular Genetics have built a series of chimeric antigen receptor (CAR)-T cells that target different antigens and secrete different anti-angiogenic proteins. Additionally, researchers also constructed bispecific CARs that respond to tumor antigen and pro-angiogenic molecules. BACKGROUND:...
Published: 2/14/2025   |   Inventor(s): Yvonne Chen
Keywords(s): Cancer, Cancer Immunotherapy, CAR-T cell therapy, immunosuppression, Immunosuppressive Drug, Immunotherapy, solid tumors, Tumor microenvironment, tumor vasculature, VEGF
Category(s): Therapeutics > Oncology
Object-Detecting Deep Learning for Multi-Event Electrochemical Data (Case No. 2024-088)
Summary: UCLA researchers in the Department of Chemistry and Biochemistry developed a custom-designed deep learning architecture for object detection and mechanisms classification to streamline the experimental design of cyclic voltammograms. Background: Cyclic voltammetry, a widely used electrochemical test, serves as a crucial tool in understanding...
Published: 2/14/2025   |   Inventor(s): Chong Liu, Quanquan Gu, Benjamin Hoar, Weitong Zhang, Yuanzhou Chen
Keywords(s): 2D ultrasound imaging, Artifical Intelligence (Machine Learning, Data Mining), artificial electromagnetic materials, bioelectronics, Biomaterial, electrochemical sensors, Electronics & Semiconductors, Lithium Battery, Lithium-Ion Battery, Machine Learning, Materials, Medical Devices and Materials, Medical diagnostics, Pharmaceutical Drug, Pharmaceutical testing, Rechargeable Battery, zzenergy storage
Category(s): Electrical > Electronics & Semiconductors, Energy & Environment > Energy Efficiency, Energy & Environment > Energy Storage, Energy & Environment > Water Monitoring & Treatment, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Electrical > Signal Processing
Speaking Without Vocal Folds Using Machine-Learning-Assisted Wearable Sensing-Actuation Systems (Case No. 2024-087)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel, machine learning-assisted wearable loudspeaker to capture and translate muscle movement into audible speech. Background: Dysphonia, or the impairment of voice production, is commonly caused by disorders of the vocal folds or postoperative recovery of laryngeal...
Published: 2/14/2025   |   Inventor(s): Jun Chen
Keywords(s):  
Category(s): Electrical, Electrical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems
A Wearable On-Eyelid Sensor Network for Vestibular-Ocular Reflex Assessment (Case No. 2023-166)
Summary: UCLA researchers in the Department of Bioengineering have developed an ultra-thin, self-powered, waterproof, biocompatible, and sensitive on-eyelid sensor network for wireless eye movement detection, enhancing vestibular diagnostics. Background: The human balance system relies on the interaction of the vestibular system with the visual and...
Published: 2/14/2025   |   Inventor(s): Jun Chen, Jing Xu
Keywords(s): diseases of the eye, eye motion, eye movement disorders, eye tracking, gaze fixation, magnetoelastic effect, magnetoelastic sensor, on-eyelid sensor, peripheral vestibular disorders, vestibular pathology assessment, Vestibular-Ocular Reflex (VOR)
Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics, Electrical, Electrical > Signal Processing, Electrical > Sensors
Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of biomarkers in bodily fluids....
Published: 2/14/2025   |   Inventor(s): Aydogan Ozcan, Hyouarm Joung, Hyun-June Jang, Junhong Chen
Keywords(s): Biomarker, biomarkers, Biomaterial, Biosensor, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Electrical, Electrical Engineering, electrically-mediated sensing, electrochemical sensors, enzyme functionalization, field-effect transistors (FETs), Medical diagnostics, multiplexed analysis, Point Of Care, point-of-care, porous media, sample matrix effects, transistors
Category(s): Electrical, Electrical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms, Platforms > Diagnostic Platform Technologies
1 2 3 4 5 6 7