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Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)

Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...

Published: 10/1/2025 | Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun

Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery

Optical Generative Models (Case No. 2025-067)

Summary: Researchers in the UCLA Department of Electrical and Computer Engineering have developed an optics-based system to rapidly generate synthetic images. Background: Generative AI models that create synthetic images, human-like natural language processing capabilities, and even new protein designs are critical for a diverse array of applications....

Published: 10/1/2025 | Inventor(s): Aydogan Ozcan, Shiqi Chen

Keywords(s): Adaptive Optics, all-optical diffractive computing, Electro-Optics, Optical Coherence , Optical computing, Optical Generative Models, Optics

Category(s): Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Optics & Photonics, Electrical, Electrical > Signal Processing, Electrical > Imaging, Electrical > Visual Computing

Pulse Laser Driven High Speed, On-Demand, and Multiplexed Droplet Generator (Case No. 2013-184)

Summary UCLA researchers have developed a high-speed, on-demand microfluidic droplet platform that allows rapid and precise generation, manipulation, and merging of microdroplets for advanced lab-on-a-chip applications. The technology enables controlled droplet initiation and synchronized merging at high throughput, making it a versatile platform for...

Published: 9/24/2025 | Inventor(s): Pei-Yu Chiou, Michael Teitell, Ting Hsiang Wu, Yue Chen, Yu Chun Kung

Keywords(s):

Category(s): Optics & Photonics, Optics & Photonics > Lasers, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Research Methods, Life Science Research Tools > Cell Counting And Imaging

TYRP-1 Chimeric Antigen Receptor to Treat Melanoma (UCLA Case No. 2020-106)

UCLA researchers in the Departments of Surgical Oncology and Microbiology, Immunology, & Molecular Genetics. have developed a CAR-T therapy that targets TYRP-1 for the treatment of melanoma. BACKGROUND: Immune checkpoint blockade (ICB) is a rapidly emerging immunotherapy approach that uses patients’ immune cells to treat cancer. In contrast...

Published: 9/15/2025 | Inventor(s): Cristina Puig Saus, Antoni Ribas, Yvonne Chen

Keywords(s): Gene Therapy, Hematology, Immunotherapy, Research Methods

Category(s): Therapeutics > Hematology

Self-Powered Electrical Stimulation Magnetoelastic Bandage for Accelerated Wound Healing (Case No. 2025-99N)

Reference: UCLA Case No. 2025-99N Please reach out to our office for more information.

Published: 10/10/2025 | Inventor(s): Jun Chen, Kanishk Rai, Song Li, Il Woo Ock, Haochen Nan

Keywords(s):

Category(s): Therapeutics, Therapeutics > Aesthetic Medicine, Materials, Materials > Functional Materials, Materials > Membranes, Electrical, Electrical > Flexible Electronics

Contact Status and Position Sensing System for Mechanical Structures (Case No. 2025-275)

Contact Status and Position Sensing System for Mechanical Structures Potential applications: manufacturing, aerospace, biomechanical devices, robotics, defense. Please reach out to our office for more information.

Published: 10/6/2025 | Inventor(s): Tyler Clites, Dean Chen

Keywords(s):

Category(s): Mechanical, Mechanical > Sensors, Mechanical > Robotics, Materials, Mechanical > Manufacturing

A Smart Pen for Parkinson’s Disease Diagnostics (Case No. 2025-283)

Summary UCLA researchers have developed a smart pen for Parkinson’s Disease (PD) diagnostics that converts handwriting motions—both on paper and in air—into high-fidelity voltage signals for accurate, accessible, and low-cost disease screening. This pen leverages magnetoelastic sensing and ferrofluid ink to enable self-powered, quantitative...

Published: 9/12/2025 | Inventor(s): Jun Chen, Guorui Chen

Keywords(s):

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Medical Devices > Hospital Systems, Diagnostic Markers, Diagnostic Markers > Aging

A Smart Pen for Parkinson’s Disease Diagnostics (Case No. 2025-283)

Published: 9/12/2025 | Inventor(s): Jun Chen, Guorui Chen

Keywords(s):

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Medical Devices > Hospital Systems, Diagnostic Markers, Diagnostic Markers > Aging

Co-Deacidification and Dechlorination of Aqueous/Gaseous Streams by Mineral Dissolution (Case No. 2022-173)

Summary UCLA researchers have developed a method and composition for simultaneous deacidification and dechlorination of acidic aqueous solutions (including brines or electrolyte streams enriched in free-chlorine species), using mineral or rock solids containing low-valent metals to neutralize acidity and remove chlorine contaminants. Background Electrolytic...

Published: 9/11/2025 | Inventor(s): Gaurav Sant, David Jassby, Xin Chen, Dante Simonetti, Steven Bustillos

Keywords(s):

Category(s): Materials, Materials > Functional Materials, Materials > Membranes, Materials > Nanotechnology, Energy & Environment

Ultrasonic Process for Selective Extraction of Lithium and Magnesium From Suitable Geological Precursors and Alkaline Indust (Case No. 2022-135)

Summary UCLA researchers have developed new methods for designing and synthesizing inorganic porous materials and extracting valuable metal ions from natural and waste sources. The first technology uses metal cations as inorganic structure-directing agents to control the formation of zeolite (phillipsite) and silicate hydrate (tobermorite) phases without...

Published: 9/11/2025 | Inventor(s): Gaurav Sant, Ross Arnold, Mathieu Bauchy, Dante Simonetti, Xin Chen, David Jassby, Lawrence Anovitz, Elena Tajuelo Rodriguez

Keywords(s):

Category(s): Materials, Materials > Metals, Materials > Functional Materials, Energy & Environment

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