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Synthetic Exosomes (SE) for CNS Delivery of CRISPR for Gene Editing in Brain Disorders (UCLA Case No. 2021-363)
UCLA researchers from the Department of Neurology have developed synthetic exosomes, a novel delivery technology capable of transporting gene-editing tools and therapeutics across the blood-brain barrier, with successful applications in repairing Alzheimer’s-related mutations and delivering proteins, antibodies, and drugs. BACKGROUND: The emergence...
Published: 2/18/2025
|
Inventor(s):
Varghese John
Keywords(s):
Alzheimers disease
,
CRISPR
,
delivery system
,
exosome
,
Nanotechnology
,
nanovesicles
,
synthetic biology
Category(s):
Life Science Research Tools > Microfluidics And Mems
,
Materials > Nanotechnology
,
Platforms > Drug Delivery
,
Therapeutics > Gene Therapy And Editing
,
Therapeutics > CNS and Neurology
HgTe Quantum Dots With Near Untiy Photoluminescent Quantum Yields in the Near and Short-Wave Infrared (Case No. 2024-256)
Summary: Researchers in UCLA’s Department of Chemistry and Biochemistry have developed an innovative synthesis technique to create ultrasmall Mercury Telluride (HgTe) quantum dots, offering tunable optoelectronic properties and high photoluminescent quantum yields across the infrared spectrum. Background: HgTe quantum dots are gaining popularity...
Published: 2/14/2025
|
Inventor(s):
Justin Caram
,
Belle Coffey
Keywords(s):
Biochemistry
,
Chemical
,
Electronics & Semiconductors
,
Imaging
,
Infrared
,
infrared thermal imaging
,
Light-Emitting Diode
,
Materials
,
Microscale Chemistry
,
Nanomaterials
,
nanophotonics
,
near-infrared
,
Optoelectronic materials
,
Optoelectronics
,
photodetection
,
photoluminescence
,
photostability
,
Quantum Dot
,
Semiconductor
,
Semiconductors
Category(s):
Electrical > Imaging
,
Chemical
,
Optics & Photonics
,
Materials > Nanotechnology
,
Chemical > Instrumentation & Analysis
,
Electrical > Sensors
,
Materials > Semiconducting Materials
Directly Sprayed 2D Nanomaterial Coatings on Body Surfaces for Health Monitoring (Case No. 2025-051)
Summary: UCLA researchers from the Department of Chemistry and Biochemistry have developed a novel coating that is directly sprayed on body surfaces for improved health monitoring, particularly for deep tissues. Background: Deep tissue activities, such as blood circulation and brain function, provide crucial insight into normal and pathological...
Published: 2/14/2025
|
Inventor(s):
Xiangfeng Duan
,
Yu Huang
,
Dehui Zhang
Keywords(s):
Category(s):
Electrical
,
Electrical > Flexible Electronics
,
Electrical > Sensors
,
Materials
,
Materials > Nanotechnology
,
Medical Devices
,
Medical Devices > Monitoring And Recording Systems
A Tissue-Like Multimodal Neural Probe (Case No. 2024-108)
Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel self-softening and biocompatible polymer to be used in a neural probe. Background: Implantable bioelectronics are revolutionizing the diagnosis and treatment of neurological and neuropsychiatric disorders. Compared with noninvasive approaches,...
Published: 3/7/2025
|
Inventor(s):
Anne Andrews
,
Qibing Pei
,
Zhixin Xie
,
Chuanzhen Zhao
Keywords(s):
bioelectronics
,
neural stimulation
,
Neuroimaging
,
Neurointervention
,
neurological disorders
,
Neuromodulation
,
Neuropsychological Test
,
Polymer
,
Smart Material
,
soft robotics
,
thermal stability
,
Tissue (Biology)
Category(s):
Chemical
,
Chemical > Polymers
,
Medical Devices > Neural Stimulation
,
Therapeutics > CNS and Neurology
,
Materials > Nanotechnology
Carbon-Negative Desalination With High-Value Materials Recovery (Case No. 2024-008)
Summary: Researchers led by Dr. Eric Hoek have developed a carbon-negative method to desalinate brine and seawater and extract valuable materials from the source solution. Background: Increased global temperatures and extreme droughts are driving water shortages throughout the world. To address this, water recycling and desalination efforts have...
Published: 2/14/2025
|
Inventor(s):
Eric Hoek
,
Sungtaek Ju
,
Yoram Cohen
,
David Jassby
Keywords(s):
brine
,
brine concentrate
,
carbon negative
,
carbon neutral
,
carbon sequestration
,
Desalination Wastewater
,
Energy & Water
,
freshwater generation
,
global carbon utilization
,
Half-Reaction Electrolysis Of Water Oxygen Evolution
,
Membrane bioreactor
,
membrane fouling
,
membrane scaling
,
Membranes
,
mineral harvesting
,
nanofiltration
,
renewable fuel
,
reverse osmosis (RO)
,
Seawater
,
treatment efficacy
,
Wastewater treatment
,
Water Injection (Oil Production)
,
Water Purification, Nanofiltration, Ultrafiltration
,
water recovery
,
Water treatment
Category(s):
Chemical
,
Chemical > Chemical Processing & Manufacturing
,
Energy & Environment
,
Energy & Environment > Energy Generation
,
Energy & Environment > Water Monitoring & Treatment
,
Energy & Environment > Carbon Capture
,
Energy & Environment > Energy Efficiency
,
Materials
,
Materials > Nanotechnology
,
Materials > Water Treatment
,
Materials > Membranes
Electrically Gated Solid-State Molecular Thermal Transistor (Case No. 2024-099)
Summary: UCLA researchers have introduced a solid-state thermal transistor that achieves groundbreaking performance and facilitates improved heat flow manipulation. Background: The forefront of thermal management is marked by the exploration of molecular thermal transistors, driven by the quest for more efficient electronic devices. Researchers are...
Published: 2/14/2025
|
Inventor(s):
Yongjie Hu
,
Paul Weiss
,
Man Li
Keywords(s):
; self-assembled molecule
,
Composite Material
,
Doping (Semiconductor)
,
Elastic Modulus Thermal Grease
,
Electronics & Semiconductors
,
field-effect transistors (FETs)
,
Functional Materials
,
heat control
,
heat controlling devices
,
infrared thermal imaging
,
Microelectronics Semiconductor Device Fabrication
,
molecular design
,
molecular engineering
,
molecular junction
,
Nanomaterials
,
Optoelectronic materials
,
Optomechanical Thermal Imaging Transducer
,
organic field effect transistors
,
Organic Semiconductor
,
phase change materials
,
Rechargeable Battery Thermal Conductivity
,
self-assembled molecule
,
Semiconductor
,
semiconductor chip foundries
,
Semiconductor Device
,
Semiconductor Device Fabrication
,
Semiconductor Ohmic Contact
,
Semiconductor Risk Assessment
,
Semiconductor Sapphire
,
Semiconductors
,
solid-state thermal transistor
,
strength-thermal stability
,
switching reversibility
,
thermal circuit
,
thermal compression bonding
,
thermal conductance
,
Thermal Energy Storage
,
thermal fusion
,
thermal imaging
,
thermal management systems
,
thermal stability
,
thermal switching speed
,
thermal switching speeds
,
thermal transistor
,
Thin-Film Transistor
,
Transistor
,
transistors
,
zzsemiconducting materials
Category(s):
Electrical
,
Electrical > Electronics & Semiconductors
,
Energy & Environment
,
Energy & Environment > Energy Generation
,
Energy & Environment > Energy Storage
,
Energy & Environment > Energy Transmission
,
Energy & Environment > Thermal
,
Electrical > Instrumentation
,
Materials
,
Materials > Nanotechnology
Nanotechnology-Enabled Reduction of Fusion-Induced Residual Stress in Alloys (Case No. 2024-225)
Summary: UCLA researchers in the Departments of Mechanical & Aerospace Engineering and Materials Science & Engineering have developed a novel method for stress reduction in welded alloy materials. Title: Nanotechnology-Enabled Reduction of Fusion-Induced Residual Stress in Alloys Background: Fusion welding is commonly used in manufacturing...
Published: 3/4/2025
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Inventor(s):
Xiaochun Li
,
Nar Murali
Keywords(s):
Alloy
,
metal nanocomposites
,
Metal process monitoring
,
Metalation
,
Metallurgy
,
Metals
,
nanocrystalline metals
,
nanograined metals
Category(s):
Materials
,
Materials > Metals
,
Materials > Fabrication Technologies
,
Materials > Nanotechnology
Discovering Permanent Fluidic Magnets for Liquid Bioelectronics (Case No. 2024-083)
Summary: UCLA researchers from the Department of Bioengineering have developed a permanent fluidic magnet that maintains stable colloids for application in a variety of fields, including physiological monitoring and bioelectronics. Background: Colloid suspensions are comprised of dispersed small solid particles in fluids. The stability of a colloid...
Published: 3/20/2025
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Inventor(s):
Jun Chen
Keywords(s):
Category(s):
Materials
,
Materials > Functional Materials
,
Materials > Membranes
,
Electrical
,
Electrical > Mems
,
Materials > Nanotechnology
,
Platforms
,
Platforms > Drug Delivery
Dynamic Extension of the Eyebox for Maxwellian View AR Waveguides (Case No. 2024-163)
Summary: Researchers in the Department of Electrical & Computer Engineering have developed a new metasurface material that improves the size and resolution of augmented reality overlays. Background: Augmented reality (AR) waveguide displays have revolutionized the way users can interact with virtual content overlaid in the real world. High...
Published: 2/14/2025
|
Inventor(s):
Chee Wei Wong
,
Hyunpil Boo
Keywords(s):
artificial electromagnetic materials
,
artificial-intelligent materials
,
Augmented Reality
,
augmented reality (AR)
,
bacterial nanocellulose
,
Carbon Nanotube
,
Composite Materials
,
Construction Materials
,
Extended reality
,
Functional Materials
,
intercalated materials
,
liquid crystal nanofibers
,
Materials
,
Medical Devices and Materials
,
meta materials
,
metal nanocomposites
,
metasurfaces
,
microarchitectured materials
,
Microfluidics Nanosphere
,
Mixed Reality
,
nanobody
,
nanocomposite scintillators
,
Nanocomposites
,
Nanocrystal
,
nanocrystalline metals
,
nanodispersion
,
Nanoelectronics
,
Nanoemulsion droplet
,
Nanofiber
,
nanograined metals
,
Nanomaterials
,
Nanoparticle
,
Nanoparticles
,
nanophotonic
,
nanophotonic structures
,
nanophotonics
,
Nanosensor
,
Nanostructure
,
nanostructured materials
,
Nanotechnology
,
Optoelectronic materials
,
photonic materials
,
Raw materials supplier
,
Toxicity Of Nanomaterials
,
Ultrahard materials/abrasives
,
Virtual Reality
,
Virtual Reality Braille Haptic Technology Joule Heating
,
Virtual Reality Occupational Therapy Exercise Machine
,
Water Purification, Nanofiltration, Ultrafiltration
,
zzsemiconducting materials
Category(s):
Software & Algorithms
,
Software & Algorithms > Ar/Vr
,
Materials
,
Materials > Composite Materials
,
Materials > Functional Materials
,
Materials > Nanotechnology
Optoelectronic Neuron Array for Nonlinear Optical Modulation and AI Cameras (Case No. 2023-208)
Summary: UCLA researchers in the Departments of Chemistry & Biochemistry and Materials Science & Engineering have developed a novel optoelectronic neuron array for computational imaging and sensing applications that can work under weak broadband incoherent light. Background: Nonlinear optical processing of ambient light is desirable for...
Published: 2/14/2025
|
Inventor(s):
Xiangfeng Duan
,
Aydogan Ozcan
,
Dehui Zhang
Keywords(s):
Category(s):
Software & Algorithms
,
Software & Algorithms > Image Processing
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Materials
,
Materials > Nanotechnology
,
Electrical
,
Electrical > Signal Processing
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