Search Results - platforms+%3e+drug+delivery

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A Ventilated Artificial Human Lung Exposure System to Analyze and Test Human Exposures to Inhaled Substances (Case No. 2023-306)

Summary: UCLA researchers in the Department of Medicine and Environmental Health Sciences have developed a ventilated human lung system for laboratory testing of inhaled substances. Background: Measuring the toxicology of inhaled air, aerosols and other substances is challenging due to the complexity of human studies and limitations in existing...

Published: 3/27/2025 | Inventor(s): Michael Roth, Airi Harui, Yifang Zhu, Haoxuan Chen

Keywords(s): aerosol, Angiogenesis Acute Lung Injury, bioaerosol, cardiopulmonary illness, Cellular Respiration, consumer goods and products, Lung, Lung Pulmonology, non-small cell lung cancer, Preclinical model development, Preclinical surgical innovation, pulmonary arterial pressure (PAP), pulmonary failure, Pulmonary fibrosis, Respiratory & Pulmonary, respiratory failure, right atrial to pulmonary canula, Simulation & Modeling, simulation model, small cell lung cancer

Category(s): Platforms, Platforms > Drug Delivery, Life Science Research Tools, Life Science Research Tools > Research Methods, Therapeutics, Therapeutics > Respiratory And Pulmonary, Mechanical, Mechanical > Sensors

Synthetic Exosomes (SE) for CNS Delivery of CRISPR for Gene Editing in Brain Disorders (UCLA Case No. 2021-363)

UCLA researchers from the Department of Neurology have developed synthetic exosomes, a novel delivery technology capable of transporting gene-editing tools and therapeutics across the blood-brain barrier, with successful applications in repairing Alzheimer’s-related mutations and delivering proteins, antibodies, and drugs. BACKGROUND: The emergence...

Published: 2/18/2025 | Inventor(s): Varghese John

Keywords(s): Alzheimers disease, CRISPR, delivery system, exosome, Nanotechnology, nanovesicles, synthetic biology

Category(s): Life Science Research Tools > Microfluidics And Mems, Materials > Nanotechnology, Platforms > Drug Delivery, Therapeutics > Gene Therapy And Editing, Therapeutics > CNS and Neurology

A Novel “Host-Guest”-Based Supramolecular Hydrogel for Dental Pulp Regeneration (Case No. 2023-154)

Summary: Researchers in the Department of Dentistry at UCLA have developed an innovative hydrogel for a vast array of biomedical and tissue engineering applications. Background: Hydrogels have emerged as powerful tools in biomedical engineering due to their ability to provide a supportive environment for cell growth, tissue repair, and drug delivery....

Published: 3/20/2025 | Inventor(s): Alireza Moshaverinia, Weihao Yuan

Keywords(s): anti-dehydration, Drug Delivery, dynamic identification, hydrogel, Stem Cells / Regenerative Medicine, Targeted Therapy, tissue regeneration

Category(s): Chemical, Materials > Functional Materials, Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Platforms > Drug Delivery > Nanoparticles, Platforms > Drug Delivery > Viral Delivery Systems, Therapeutics > Cell Therapy, Therapeutics > Medication, Therapeutics > Stem Cells And Regenerative Medicine

Compound Drug Delivery System (Case No. 2024-015)

Summary: Researchers in UCLA’s Department of Orthopaedic Surgery have developed novel multi-drug delivery system that is compatible with standard syringe-based administration routes. Background: Drug compounding is the process of combining two or more medications to meet the needs of individual patients. Surgeons may mix different anesthetics...

Published: 3/20/2025 | Inventor(s): Fabrizio Billi, Mauricio Silva, Aaron Kavanaugh

Keywords(s):

Category(s): Therapeutics, Platforms, Platforms > Drug Delivery, Medical Devices

A Bistable Deformable Tactile Responsive Material and Device (Case No. 2024-202)

Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel electroactive polymer membrane composition for interactive tactile interfaces. Background: Interactive tactile interfaces are soft actuators with diverse applications in medical and surgical training, actively deformable apparel, refreshable Braille...

Published: 2/14/2025 | Inventor(s): Qibing Pei, Jinsung Kim, HyeonJi Hong

Keywords(s): bistable electroactive polymer, Braille, BSEP, deformable geometries, diaphragms, elastomers, hybrid electrodes, joule heating, MCRB, multi-cell refreshable Braille, phase change materials, shape memory, soft actuator, Stretchable electrodes

Category(s): Materials, Materials > Functional Materials, Medical Devices, Platforms, Platforms > Drug Delivery

Discovering Permanent Fluidic Magnets for Liquid Bioelectronics (Case No. 2024-083)

Summary: UCLA researchers from the Department of Bioengineering have developed a permanent fluidic magnet that maintains stable colloids for application in a variety of fields, including physiological monitoring and bioelectronics. Background: Colloid suspensions are comprised of dispersed small solid particles in fluids. The stability of a colloid...

Published: 3/20/2025 | Inventor(s): Jun Chen

Keywords(s):

Category(s): Materials, Materials > Functional Materials, Materials > Membranes, Electrical, Electrical > Mems, Materials > Nanotechnology, Platforms, Platforms > Drug Delivery

Targeted Delivery of IFN-gamma Using Antibody Fusion Proteins (UCLA Case No. 2017-543)

UCLA researchers in the Departments of Microbiology, Immunology & Molecular Genetics (MIMG) and Medicine have developed antibody–cytokine fusion proteins that enable the targeted delivery of active interferon-gamma (IFNγ) for cancer treatment. Interferon-gamma (IFNγ), a type II interferon, is a cytokine released by both natural...

Published: 2/14/2025 | Inventor(s): Sherie Morrison, John Timmerman, Kham (Ryan) Trinh

Keywords(s): Antibody Delivery Platforms, Drug Delivery, Immunotherapy, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Therapeutics, Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Life Science Research Tools, Therapeutics > Immunology And Immunotherapy

Intelligent Stent System for Chronic On-Demand Drug Delivery (Case No. 2021-069)

Summary: UCLA researchers in the Department of Neurology have developed an intelligent stent system for chronic on-demand drug delivery, addressing the challenge of the blood-brain barrier hindering drug therapy in the central nervous system. Background: The blood-brain barrier poses a significant obstacle to effective drug delivery to the central...

Published: 2/14/2025 | Inventor(s): Jose Morales, Haotian Lu, Huachen Cui, Xiaoyu Zheng

Keywords(s): blood flow management, blood-brain barrier, Drug, Drug Delivery, Drug monitoring, Invasiveness Of Surgical Procedures, MEMS, minimally invasive device, minimally invasive drug delivery systems, neural signals, neural stimulation, Neurocognitive, Neurodegeneration, neurological disorders, Neurology, neuro-oncology, Neuropathology, Neurosurgery, non-invasive, non-invasive drug monitoring, on-demand drug delivery, Pharmaceutical Drug, piezoelectric ultrasound transducers

Category(s): Platforms, Platforms > Drug Delivery, Medical Devices, Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Oncology, Therapeutics > Musculoskeletal Disease

2022-165 Development of a Silicasome Drug Nanocarrier System to Deliver a Lipid Bilayer-Encapsulated TLR7 Agonist for Cancer Immunotherapy

SUMMARY: UCLA researchers in the Department of Medicine have developed a scalable and injectable drug delivery platform that allows for tumor-specific combinatorial cancer immunotherapy treatment of pancreatic cancer. BACKGROUND: The National Institute of Health reports that pancreatic ductal adenocarcinomas (PDAC) accounts for at least 90% of all...

Published: 2/14/2025 | Inventor(s): Andre Nel

Keywords(s):

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Nanoparticles, Therapeutics > Oncology

2022-223 A Bioanalytics-Enabled and Hollow Microneedle-Based Wearable Technology for Personalized Medicine

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a minimally-invasive wearable device that continuously monitors pharmaceutical concentrations in a user to optimize the drug’s dosage. Background: The annual cost of medication-related morbidity and mortality due to non-optimized pharmacotherapy...

Published: 2/14/2025 | Inventor(s): Sam Emaminejad, Shuyu Lin

Keywords(s): Adverse Drug Reaction, Antibody-Drug Conjugate, Antiviral Drug, Biomonitoring, Blood Glucose Monitoring, Drug, Drug Carrier, Drug Delivery, Drug Delivery Microporous Material, Drug Development, Drug Development Feature Extraction, Drug Discovery, Drug monitoring, Drug Resistance, Drug-Eluting Stent, Extensively Drug-Resistant Tuberculosis, Fine-Needle Aspiration, Gene Combination Drug, Immunosuppressive Drug, interstitial fluid (ISF)-based information, Investigatioal New Drug, Management Of HIV/AIDS Psychoactive Drug, medical automation technology, Medical Device, Medical Devices and Materials, medication customization, medication efficacy, Microneedle array, minimally invasive device, Monitoring (Medicine), Monitoring And Recording Systems, Multiple Drug Resistance, Mutation Drug Design, Nanosensor, Nanostructure, Nanotechnology, non-invasive drug monitoring, personalized dose assessment, Pharmaceutical Drug, Pharmaceutical Drug Ethylene Glycol, Pharmaceutical Drug Opioid Dependence, Prescription Drug, real-time sensing/monitoring/tracking, remote monitoring, sample-to-answer devices, Smart medical device, Therapeutic Drug Monitoring, wearable medical device

Category(s): Mechanical, Mechanical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms > Drug Delivery, Software & Algorithms > Bioinformatics, Software & Algorithms > Artificial Intelligence & Machine Learning, Electrical > Sensors, Materials > Nanotechnology

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