Search Results - yang+yang

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Through-Glass Vias (TGVS) Thermal Management Using Diamond-Assisted Copper Metallization for Advanced 3DIC Packaging (Case No. 2026-156)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel approach to enhance the thermal performance of through-glass vias for advanced semiconductor packaging. Background: Advanced semiconductor systems rely on 3D integrated circuits (3DICs) to meet rising demands for higher performance, reduced...

Published: 2/23/2026 | Inventor(s): Tiwei Wei, Ye Yang

Keywords(s): 3D integrated circuits (3DIC), advanced semiconductor packaging, artificial intelligence accelerators, copper electroplating, cubic-octahedral diamond, diamond composites, diamond metallization, Doping (Semiconductor), Electronics & Semiconductors, ferromagnetic semiconductor, functional/composite materials, glass interposers, heat dissipation, high-performance computing, Microelectronics Semiconductor Device Fabrication, microfabrication, Organic Semiconductor, physical vapor deposition (PVD), real-time thermal management, Semiconductor, semiconductor chip foundries, Semiconductor Device, Semiconductor Device Fabrication, Semiconductor Ohmic Contact, Semiconductor Risk Assessment, Semiconductor Sapphire, Semiconductors, silicon interposers, thermal bottleneck, thermal management, thermal management systems, through-glass vias (TGVs), zzsemiconducting materials

Category(s): Chemical, Chemical > Industrial & Bulk Chemicals, Chemical > Synthesis, Chemical > Chemical Processing & Manufacturing, Electrical, Electrical > Computing Hardware, Electrical > Electronics & Semiconductors, Materials, Materials > Metals, Materials > Semiconducting Materials, Materials > Functional Materials, Materials > Fabrication Technologies, Materials > Composite Materials, Software & Algorithms > Communication & Networking

Indole-3-Propionic Acid (IPA) Protects Against Heart Failure with Preserved Ejection Fraction (HFpEF) (UCLA Case No. 2022-142)

UCLA researchers in the Department of Medicine, Division of Cardiology have identified the protective effects of gut-heart crosstalk mediated by 3-propionic acid (IPA) in the progression of heart failure with preserved ejection fraction (HFpEF). IPA supplementation could rescue the IPA deficiency associated heart defects, protect against heart malfunction,...

Published: 2/26/2026 | Inventor(s): Aldons Lusis, Yang Cao

Keywords(s):

Category(s): Therapeutics > Cardiovascular

Coagulation Factor XI (FXI) Functional Roles and Regulation for Treatment of Heart Failure (UCLA Case No. 2022-141)

UCLA researchers from the Department of Medicine have discovered a novel therapeutic target to treat heart failure with preserved ejection fraction (HFpEF), which afflicts approximately half of all patients with heart failure. BACKGROUND: Heart failure is one of the leading causes of death and disease with over 500,000 cases diagnosed each year in...

Published: 2/26/2026 | Inventor(s): Aldons Lusis, Yang Cao

Keywords(s):

Category(s): Therapeutics > Cardiovascular, Therapeutics > Metabolism And Endocrinology

Microfluidic Lab-on-Chip Device, Small Molecules and Three-Dimensional Spheroids for Cell Reprogramming (UCLA Case No. 2020-881)

UCLA researchers in the Department of Bioengineering at Samueli School of Engineering developed bioengineering approaches that can significantly promote cell reprogramming with higher efficiency. This invention is important for basic science, disease modeling, therapeutic testing, and cell engineering for regenerative medicine applications. BACKGROUND:...

Published: 2/26/2026 | Inventor(s): Song Li, Yang Song

Keywords(s):

Category(s): Life Science Research Tools > Microfluidics And Mems

Hyperbranched Polyglycerol Encapsulated Proteins for Oral Protein Delivery (Case No. 2012-425)

Patent Abstract: Methods for modifying therapeutic agents such as therapeutic biomolecules, such as proteins for improved oral, rectal or transmucosal delivery, as well as compositions made using such methods and methods of administering such compositions to a subject, are disclosed. Specifically, the therapeutic agents are conjugated to hyperbranched...

Published: 12/1/2025 | Inventor(s): Yunfeng Lu, Juanjuan Du, Jie Li, Yang Liu

Keywords(s):

Category(s): Platforms > Drug Delivery

Compliant Mechanisms That Perform Mathematical Operations via Analog Computing (Case No. 2025-230)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a fully compliant mechanism that performs mathematical operations using analog computing. Background: Mechanical computers rely on the relative motion of physical bodies to perform computations, rather than electronic signals, as electrical computers...

Published: 11/18/2025 | Inventor(s): Jonathan Hopkins, Pietro Sainaghi, Alexander Tsao, Zhidi Yang

Keywords(s): Advanced Computing / AI, Aerospace, Aerospace Engineering, analog computing, analog optical computing, computational efficiency, feature space, low latency computing, space compatible inks, Space Shuttle, Spacecraft

Category(s): Mechanical, Mechanical > Aeronautics & Aerospace, Mechanical > Instrumentation, Mechanical > Mechanical Systems, Mechanical > Micro-Electromechanical Systems (Mems), Mechanical > Sensors, Materials, Materials > Functional Materials

IL-2 Independent Ultrahigh Human T Cell Activations Through Biomimetics of Immune Synapses by Graphene Oxides (UCLA Case No. 2021-068)

UCLA researchers in the Department of Materials Science and Engineering have constructed a novel graphene oxide-based platform for robust T cell activation through artificial immune synapse formation. BACKGROUND: T cells are a critical arm of the immune system with tremendous therapeutic value for immune disorders and cancer. However, modulation of...

Published: 10/2/2025 | Inventor(s): Yu Huang, Lili Yang

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

Multilevel Buffered Link (Case No. 2025-284)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel on-chip link that enhances communication performance and energy efficiency in modern integrated circuits. Background: On-chip communication enables data transfer between microchip components and is critical in computing, automotive, and industrial...

Published: 11/17/2025 | Inventor(s): Sudhakar Pamarti, Chih-Kong Yang, Haris Suhail

Keywords(s): Bandwidth (Signal Processing), buffer layer, Clock Signal, efficiency bandwidth products, Electrical, Electrical Engineering, Energy Efficiency, energy efficient IoT, energy-efficient, high-data-rate links, high-speed communications, IoT communication, large bandwidth, low-power device, Network On A Chip, scalable communication, scalable fabrication, Signaling pathways, Signal-To-Noise Ratio, System On A Chip

Category(s): Electrical, Electrical > Electronics & Semiconductors > Circuits, Electrical > Computing Hardware, Software & Algorithms > Communication & Networking, Electrical > Signal Processing

Engineered Mucosal-Associated Invariant T (MAIT) Cells and Methods of Making and Using Thereof (UCLA Case No. 2024-055)

UCLA researchers in the Department of Microbiology Immunology and Molecular Genetics have developed a novel platform and methodology for the production of mucosal-associated invariant T (MAIT) cells for therapeutic use in infectious diseases, autoimmune disorders, and cancer. BACKGROUND: Mucosal-associated invariant T (MAIT) cells are a subset of...

Published: 7/31/2025 | Inventor(s): Lili Yang

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Infectious Diseases, Therapeutics > Immunology And Immunotherapy, Therapeutics > Autoimmune

Viral Vector-Based Gene Therapy for OPA1 Gene Mutation-Induced Dominant Optic Atrophy (UCLA Case No. 2025-004)

UCLA researchers in the Department of Ophthalmology have developed a viral vector-based gene therapy to restore OPA1 protein levels in patients with OPA1-mutated dominant optic atrophy. The optimized vectors will be delivered intravitreally to patients’ eyes, providing a minimally invasive, effective treatment with reduced side effects. BACKGROUND:...

Published: 11/25/2025 | Inventor(s): Xianjie Yang

Keywords(s): Adeno-associated viruses (AAV), disease model, dominant optic atrophy, Gene Therapy, intravitreal delivery, Lentivirus Viral Vector, mitochondria, mutation, Neuron, OPA1, Ophthalmology, pluripotent stem cell (PSC), retinal ganglion cell

Category(s): Therapeutics > CNS and Neurology, Therapeutics > Gene Therapy And Editing, Therapeutics > Ophthalmology

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