Search Results - diagnostic+platform+technologies+(e.g.+microfluidics)

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Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of biomarkers in bodily fluids....

Published: 4/1/2024 | Inventor(s): Aydogan Ozcan, Hyou-Arm Joung, Hyun-June Jang, Junhong Chen

Keywords(s): Biomarker, biomarkers, Biomaterial, Biosensor, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Electrical, Electrical Engineering, electrically-mediated sensing, electrochemical sensors, enzyme functionalization, Medical diagnostics, multiplexed analysis, Point Of Care, point-of-care, porous media, sample matrix effects, transistors

Category(s): Electrical, Electrical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms, Platforms > Diagnostic Platform Technologies

Core-Shell Hydrogel Particles With Tunable Porosity for Digital Nucleic Acid Assays (Case No. 2023-058)

Summary: UCLA researchers in the Department of Bioengineering have developed a novel method to perform ultra-high sensitivity, low-cost nucleic acid amplification assays utilizing porous microdroplets. Background: Nucleic acid concentration measurement is essential in biological research and diagnostics. The 2020 pandemic underscored the importance...

Published: 8/30/2023 | Inventor(s): Dino Di Carlo, Michael Thomas Alesse Bogumil

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Flow Cytometry, Medical diagnostics

Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Targets And Assays, Chemical > Emulsions, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies

Stain-Free, Rapid, and Quantitative Viral Plaque Assay Using Deep Learning and Holography (Case No. 2022-326)

Intro Sentence: UCLA researchers in the Department of Electrical and Computer Engineering have developed a rapid and stain-free quantitative assay using lens-free holography and deep learning to efficiently and cost-effectively determine the presence of viral plaque-forming units (PFUs) in samples. Background: A broad range of viruses have caused...

Published: 10/17/2024 | Inventor(s): Aydogan Ozcan, Yuzhu Li, Tairan Liu

Keywords(s): Antiviral Drug, Artifical Intelligence (Machine Learning, Data Mining), Assay, Bioassay, Computer Aided Learning, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Digital Holography, Electrical, Electrical Brain Stimulation, Electrical Breakdown, Electrical Engineering, Electrical Impedance, Electrical Load, Electrical Load Equation Of State, Electrical Resistance And Conductance, Electrical Resistivity And Conductivity, Holography, Immunoassay, Immunoassay Sense (Molecular Biology), Lentivirus Viral Vector, Machine Learning, Machine Learning Autonomous Car Gradient Descent, Machine Learning Pain Management, Machine Learning Particulates Global Climate Model, Network Analysis (Electrical Circuits), Perceptual Learning, Plasmid Trabecular Meshwork Aqueous Humour Viral Vector, Targets And Assays, Transcutaneous Electrical Nerve Stimulation, Transfection Viral Vector, Unsupervised Learning , Viability Assay, Viral Delivery Systems, Viral Envelope, Viral Load

Category(s): Diagnostic Markers, Diagnostic Markers > Targets And Assays, Electrical, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Software & Algorithms > Artificial Intelligence & Machine Learning

2012-341 Quantum Dot Enabled Detection of Escherichia Coli using a Cell-Phone

Summary: UCLA researchers in the Department of Electrical Engineering have developed a platform that can detect E. coli using a cell phone. Background: Water and food-associated diseases still pose considerable public health threat even in highly industrialized parts of the world, causing significant amount of hospitalizations and deaths every year....

Published: 7/19/2023 | Inventor(s): Aydogan Ozcan, Hongying Zhu

Keywords(s): Cell Counting/Imaging, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Image Processing, Infectious Diseases, Photonics

Category(s): Software & Algorithms > Image Processing, Diagnostic Markers, Life Science Research Tools > Cell Counting And Imaging, Platforms > Diagnostic Platform Technologies, Therapeutics > Infectious Diseases, Optics & Photonics

2020-922 A Universal Designed Protein Cage for Sensing and Responding to Any Other Protein Molecule

SUMMARY: UCLA researchers in the Department of Chemistry and Biochemistry have designed and developed a protein cage which can be easily tailored to sense other proteins, opening in response, and thus delivering enclosed biological compounds across a wide variety of applications, including biosensing, molecular diagnostics, and targeted drug delivery....

Published: 9/5/2023 | Inventor(s): Todd Yeates

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Drug Delivery

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms > Drug Delivery, Platforms > Drug Delivery > Nucleic Acid Platform Systems, Platforms > Drug Delivery > Nanoparticles, Platforms > Drug Delivery > Nucleic Acids

2020-810 Mechanical Ventilator With a Fixed Number of Orifice Plates to Generate Constant Flow Paths

Summary: UCLA researchers in the Department of Electrical and Computer Engineering & Bioengineering have developed a constant flow path mechanical ventilator used for the treatment of advanced respiratory diseases, such as acute respiratory distress syndrome (ARDS). Background: Respiratory failure leading to the need for respiratory support...

Published: 7/19/2023 | Inventor(s): Glen Meyerowitz

Keywords(s): Angiogenesis Acute Lung Injury, Cellular Respiration, Cerebrospinal Fluid, Cerebrospinal Fluid Tetramer Retinol Binding Protein, Cerebrospinal Fluid Ventricular System Bleeding, Deoxygenation, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Digital Microfluidics, Ferrofluid, Flow Device, Fluid Dynamics, Fluidics, Half-Reaction Electrolysis Of Water Oxygen Evolution, Intensive-Care Unit Vital Signs, Lung, Lung Pulmonology, Mechanical, Mechanical Engineering, Mechanical Systems, Medical Device, Medical Device Poly(Methyl Methacrylate), Medical Devices and Materials, Microfluidics, Microfluidics And Mem's, Microfluidics Dielectrophoresis, Microfluidics Multi-Band Device, Microfluidics Nanosphere, Mouse Respiratory System, Oxygen, Oxygen Saturation, Reactive Oxygen Species, Respiratory & Pulmonary, Synovial Fluid

Category(s): Mechanical, Mechanical > Mechanical Systems, Therapeutics > Infectious Diseases > COVID

2019-346 Low-Cost And Portable UV Holographic Microscope For High-Contrast Protein Crystal Imaging

Summary: UCLA researchers in the Department of Electrical Engineering have developed an on-chip UV holographic imaging microscope that offers a low-cost, portable, and robust technique to image and distinguish protein crystals from salt crystals. Background: Dual-mode microscopes composed of bright-field and ultraviolet (UV) induced fluorescence...

Published: 7/19/2023 | Inventor(s): Aydogan Ozcan, Aniruddha Ray, Mustafa Daloglu

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Life Science Research Tools, Medical Devices and Materials, Medical Imaging, Microscopy And Imaging, Monitoring And Recording Systems, Other

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Diagnostic Markers, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies

2019-002 Motility-Based Label-Free Detection of Parasites in Bodily Fluids Using Holographic Speckle Analysis and Deep Learning

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed deep learning-based, cost-effective, and portable optical devices that facilitate label-free, high-throughput and sensitive detection of motile parasites. Background: Parasitic infections are a major global public health issue, but current screening...

Published: 10/25/2023 | Inventor(s): Aydogan Ozcan, Yibo Zhang, Hatice Ceylan Koydemir

Keywords(s): Algorithm, Artificial Intelligence, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Disease, Holography, Imaging, Infection, Infectious Diseases, Infectivity, Monitoring (Medicine), Optics, Software & Algorithms

Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Life Science Research Tools, Diagnostic Markers, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > Infectious Diseases

2020-487 Early-Detection and Classification of Live Bacteria Using Time-Lapse Coherent Imaging and Deep Learning

Summary: Researchers from UCLA’s Electrical and Computer Engineering and Bioengineering Departments have invented a novel automated system that quickly detects and classifies colonies of live bacteria in water by using deep neural networks to analyze holographic images. Background: Early identification of pathogenic bacteria in food, water,...

Published: 11/15/2024 | Inventor(s): Aydogan Ozcan, Yair Rivenson, Hongda Wang, Hatice Ceylan Koydemir, Yunzhe Qiu

Keywords(s): Diagnostic Platform Technologies (E.G. Microfluidics), Hospital Systems And Devices, Imaging, Instrumentation & Analysis, Life Science Research Tools, Microscopy And Imaging

Category(s): Electrical > Instrumentation, Electrical > Imaging, Software & Algorithms, Diagnostic Markers, Software & Algorithms > Artificial Intelligence & Machine Learning

2016-219-3 SYSTEM AND METHOD FOR OPTICAL TRANSIENT LIQUID MOLDING OF MICROPARTICLES AND USES FOR THE SAME

SUMMARY: The Di Carlo group at UCLA has invented a microparticle that enables analysis of adherent cells via flow cytometry with high throughput. BACKGROUND: Traditional flow cytometry is a fluorescence-based technique used to characterize cells on a molecular level usually suspended in a fluid. However, many cells are inherently attached to matrix...

Published: 7/19/2023 | Inventor(s): Dino Di Carlo, Chueh-Yu Wu

Keywords(s): Cell Counting/Imaging, Cytometry, Diagnostic Platform Technologies (E.G. Microfluidics), Flow Cytometry, Life Science Research Tools, Microfluidics, Microfluidics And Mem's, Targets And Assays

Category(s): Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microfluidics And Mems, Platforms > Diagnostic Platform Technologies

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